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Literature DB >> 13810473

Toxic complications of treatment with 6-mercaptopurine; two cases with hepatic necrosis and intestinal ulceration.

P A CLARK, Y E HSIA, R G HUNTSMAN.

Abstract

Entities: Chemical Disease

Keywords: INTESTINE, SMALL/diseases; LIVER DISEASES/etiology; MERCAPTOPURINE/toxicology

Mesh：

Substances：
Mercaptopurine

Year: 1960 PMID： 13810473 PMCID： PMC1966646 DOI： 10.1136/bmj.1.5170.393

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

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9 in total

1. The toxic effects of 6-mercaptopurine and related compounds.

Authors: F S PHILIPS; S S STERNBERG; S HAMILTON; D A CLARKE
Journal: Ann N Y Acad Sci Date: 1954-12-06 Impact factor: 5.691

2. A clinical study of 6-mercaptopurine.

Authors: P C GAFFNEY; W M COOPER
Journal: Ann N Y Acad Sci Date: 1954-12-06 Impact factor: 5.691

3. A study of 61 leukemias treated with 6-mercaptopurine.

Authors: J BERNARD; M SELIGMANN
Journal: Ann N Y Acad Sci Date: 1954-12-06 Impact factor: 5.691

4. Summary of experience with 6-mercaptopurine.

Authors: S FARBER
Journal: Ann N Y Acad Sci Date: 1954-12-06 Impact factor: 5.691

5. A comparative study of two regimens of combination chemotherapy in acute leukemia.

Authors: E FREI; J F HOLLAND; M A SCHNEIDERMAN; D PINKEL; G SELKIRK; E J FREIREICH; R T SILVER; G L GOLD; W REGELSON
Journal: Blood Date: 1958-12 Impact factor: 22.113

6. Hepatitis in association with prolonged 6-mercaptopurine therapy.

Authors: S K McILVANIE; J D MACCARTHY
Journal: Blood Date: 1959-01 Impact factor: 22.113

7. Chemotherapy of choriocarcinoma and related trophoblastic tumors in women.

Authors: R HERTZ; D M BERGENSTAL; M B LIPSETT; E B PRICE; T F HILBISH
Journal: J Am Med Assoc Date: 1958-10-18

8. Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of leukemia and allied diseases.

Authors: J H BURCHENAL; M L MURPHY; R R ELLISON; M P SYKES; T C TAN; L A LEONE; D A KARNOFSKY; L F CRAVER; H W DARGEON; C P RHOADS
Journal: Blood Date: 1953-11 Impact factor: 22.113

9. 6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals.

Authors: D A CLARKE; F S PHILIPS; S S STERNBERG; C C STOCK; G B ELION; G H HITCHINGS
Journal: Cancer Res Date: 1953-08 Impact factor: 12.701

9 in total

12 in total

Toxic complications of treatment with 6-mercaptopurine; two cases with hepatic necrosis and intestinal ulceration.

1. The toxic effects of 6-mercaptopurine and related compounds.

2. A clinical study of 6-mercaptopurine.

3. A study of 61 leukemias treated with 6-mercaptopurine.

4. Summary of experience with 6-mercaptopurine.

5. A comparative study of two regimens of combination chemotherapy in acute leukemia.

6. Hepatitis in association with prolonged 6-mercaptopurine therapy.

7. Chemotherapy of choriocarcinoma and related trophoblastic tumors in women.

8. Clinical evaluation of a new antimetabolite, 6-mercaptopurine, in the treatment of leukemia and allied diseases.

9. 6-Mercaptopurine: effects in mouse sarcoma 180 and in normal animals.

1. Acute leukemia: a pathologic study of the causes of death in 157 proved cases.

2. Chemotherapy in Malignant Disease: The Present Position.

3. Mechanism-Driven Read-Across of Chemical Hepatotoxicants Based on Chemical Structures and Biological Data.

4. Azathioprine and 6-Mercaptopurine-induced Liver Injury: Clinical Features and Outcomes.

5. Jejunal perforation possibly induced by slow-release potassium in a patient with Crohn's disease.

6. [Significance of Australia antigen in patients after kidney transplantation].

7. Peliosis hepatis induced by 6-thioguanine administration.

8. Peliosis hepatis in recipients of renal transplants.

9. Hepatic fibrosis in a child possibly due to prolonged methotrexate.

10. A case of chronic veno-occlusive disease of the liver.