Literature DB >> 138031

[Middle ear deafness and noise trauma. Animal studies with the surface specimen technique (author's transl)].

U Leidenfrost.   

Abstract

The pertinent clinical literature concerning the research project is reviewed. The middle ear of guinea pigs was first damaged on one side (inflicting a subtotal perforation of the tympanic membrane, dislocation of the incudo-stapedial joint followed by otitis media) and the animals were then exposed to a specified narrow-band noise. The induced inner ear changes were quantified by means of cochleographic studies using the surface specimen technique. In spite of the inner ear changes due to middle ear manipulation prior to the noise exposure, the cochleographic studies revealed an obvious protective effect of the induced middle ear changes upon the inner ear during noise exposure.

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Year:  1976        PMID: 138031

Source DB:  PubMed          Journal:  Laryngol Rhinol Otol (Stuttg)        ISSN: 0340-1588


  1 in total

1.  Intra-tympanic delivery of short interfering RNA into the adult mouse cochlea.

Authors:  Naoki Oishi; Fu-Quan Chen; Hong-Wei Zheng; Su-Hua Sha
Journal:  Hear Res       Date:  2012-11-23       Impact factor: 3.208

  1 in total

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