Literature DB >> 13799605

Nature of the hormonal influence in mouse mammary cancer.

H A BERN.   

Abstract

New findings indicate that hormones may play a permissive role, rather than an inductive one, in mammary tumorigenesis. Hormones supporting normal gland development may result in the emergence of precancerous lesions; hormones maintaining such hyperplastic lesions may result in the emergence of tumors. The "inherited hormonal influence" may rest in genetically determined sensitivity of mammary tissue to somatotropin.

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Keywords:  BREAST NEOPLASMS/experimental; CARCINOMA, DUCTAL/experimental; HORMONES/pharmacology

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Year:  1960        PMID： 13799605     DOI： 10.1126/science.131.3406.1039

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  3 in total

1.  Twenty-four hour rhythm in the mitotic activity of normal mammary epithelium on normal and inverted lighting regimens.

Authors:  J M Llanos; R S Piezzi
Journal:  J Physiol       Date:  1963-03       Impact factor: 5.182

2.  Fine structural alterations in cell particles during chemical carcinogenesis. III. Selective action of hepatic carcinogens other than 3'-methyl-4-dimethylaminoazobenzene on different types of mitochondrial swelling. Effect of stimulated liver growth.

Authors:  J C ARCOS; H H GOSCH; D ZICKAFOOSE
Journal:  J Biophys Biochem Cytol       Date:  1961-05

3.  Progesterone enhancement of mammary tumor development as a model of co-carcinogenesis.

Authors:  W E Poel
Journal:  Br J Cancer       Date:  1968-12       Impact factor: 7.640
  3 in total

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