Literature DB >> 1379837

Electrochemotherapy tumor treatment is improved by interleukin-2 stimulation of the host's defenses.

L M Mir1, S Orlowski, B Poddevin, J Belehradek.   

Abstract

We have recently described a new antitumor treatment, electrochemotherapy (ECT), based on the large local potentiation of the effects of the chemotherapeutic agent bleomycin (BLM) by electric pulses (EP) delivered at the tumor site. We demonstrate here that the host's immune response participates in cure achievement. We obtain an increase of the rate of completely cured animals by injecting mice with interleukin-2 (IL-2).

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Year:  1992        PMID: 1379837

Source DB:  PubMed          Journal:  Eur Cytokine Netw        ISSN: 1148-5493            Impact factor:   2.737


  22 in total

Review 1.  [Value of galvanotherapy for localised prostate cancer].

Authors:  C Arsov; C Winter; P Albers
Journal:  Urologe A       Date:  2009-07       Impact factor: 0.639

2.  The importance of electric field distribution for effective in vivo electroporation of tissues.

Authors:  D Miklavcic; K Beravs; D Semrov; M Cemazar; F Demsar; G Sersa
Journal:  Biophys J       Date:  1998-05       Impact factor: 4.033

3.  The Effect of Millisecond Pulsed Electric Fields (msPEF) on Intracellular Drug Transport with Negatively Charged Large Nanocarriers Made of Solid Lipid Nanoparticles (SLN): In Vitro Study.

Authors:  Julita Kulbacka; Agata Pucek; Kazimiera Anna Wilk; Magda Dubińska-Magiera; Joanna Rossowska; Marek Kulbacki; Małgorzata Kotulska
Journal:  J Membr Biol       Date:  2016-05-12       Impact factor: 1.843

Review 4.  Electrochemotherapy in head and neck cancer: A review of an emerging cancer treatment.

Authors:  Armando De Virgilio; Massimo Ralli; Lucia Longo; Patrizia Mancini; Giuseppe Attanasio; Francesca Atturo; Marco De Vincentiis; Antonio Greco
Journal:  Oncol Lett       Date:  2018-07-12       Impact factor: 2.967

5.  Electrochemotherapy: aspects of preclinical development and early clinical experience.

Authors:  John O Larkin; Christopher G Collins; Simon Aarons; Mark Tangney; Maria Whelan; Seamus O'Reily; Oscar Breathnach; Declan M Soden; Gerald C O'Sullivan
Journal:  Ann Surg       Date:  2007-03       Impact factor: 12.969

6.  Electrochemotherapy for colorectal cancer with commonly used chemotherapeutic agents in a mouse model.

Authors:  S Kuriyama; M Matsumoto; A Mitoro; H Tsujinoue; T Nakatani; H Fukui; T Tsujii
Journal:  Dig Dis Sci       Date:  2000-08       Impact factor: 3.199

7.  Mathematical Models Describing Chinese Hamster Ovary Cell Death Due to Electroporation In Vitro.

Authors:  Janja Dermol; Damijan Miklavčič
Journal:  J Membr Biol       Date:  2015-07-30       Impact factor: 1.843

8.  Potentiation of electrochemotherapy by intramuscular IL-12 gene electrotransfer in murine sarcoma and carcinoma with different immunogenicity.

Authors:  Ales Sedlar; Tanja Dolinsek; Bostjan Markelc; Lara Prosen; Simona Kranjc; Masa Bosnjak; Tanja Blagus; Maja Cemazar; Gregor Sersa
Journal:  Radiol Oncol       Date:  2012-11-09       Impact factor: 2.991

9.  First clinical trial of cat soft-tissue sarcomas treatment by electrochemotherapy.

Authors:  L M Mir; P Devauchelle; F Quintin-Colonna; F Delisle; S Doliger; D Fradelizi; J Belehradek; S Orlowski
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

10.  Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy.

Authors:  L M Mir; L F Glass; G Sersa; J Teissié; C Domenge; D Miklavcic; M J Jaroszeski; S Orlowski; D S Reintgen; Z Rudolf; M Belehradek; R Gilbert; M P Rols; J Belehradek; J M Bachaud; R DeConti; B Stabuc; M Cemazar; P Coninx; R Heller
Journal:  Br J Cancer       Date:  1998-06       Impact factor: 7.640

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