Literature DB >> 13796435

The Second International Standard for heparin.

D R BANGHAM, M V MUSSETT.   

Abstract

The Second International Standard for Heparin is a hygroscopic powder which was obtained by purifying and drying a batch of commercial beef heparin powder. In an international collaborative assay it was compared with the First International Standard, which it will now replace. As a result of the assay the seven participating laboratories agreed that the potencies of the two preparations did not differ significantly and the definition of the International Unit for Heparin remains unchanged as the activity contained in 0.0077 mg of the Second International Standard for Heparin.

Entities:  

Keywords:  HEPARIN/chemistry

Mesh:

Substances:

Year:  1959        PMID: 13796435      PMCID: PMC2537890     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN: 0042-9686            Impact factor:   9.408


  7 in total

1.  The assay of heparin.

Authors:  J PRITCHARD
Journal:  J Pharm Pharmacol       Date:  1956-07       Impact factor: 3.765

2.  In vivo and in vitro comparative assays of the anticoagulant activity of dextran sulphate and heparin.

Authors:  E GRASSET; D E SCHWARTZ
Journal:  Br J Pharmacol Chemother       Date:  1955-09

3.  [New anticoagulant and antithrombotic of the heparin type, with a contribution to the problem of comparative evaluation of heparin and heparin-like substances].

Authors:  R MARX
Journal:  Arzneimittelforschung       Date:  1956-11

4.  An in vivo method for the assay of heparin.

Authors:  J E JORPES; M BLOMBACK; B BLOMBACK
Journal:  J Pharm Pharmacol       Date:  1954-10       Impact factor: 3.765

5.  On the reliability of the methods used in the assay of heparin.

Authors:  B BLOMBACK; M BLOMBACK; E V CORNELIUSSON; J E JORPES
Journal:  J Pharm Pharmacol       Date:  1953-12       Impact factor: 3.765

6.  A colorimetric method for the standardization of heparin preparations.

Authors:  F C Macintosh
Journal:  Biochem J       Date:  1941-07       Impact factor: 3.857

7.  The use of sulphated whole blood in the assay of heparin.

Authors:  S S ADAMS
Journal:  J Pharm Pharmacol       Date:  1950-11       Impact factor: 3.765

  7 in total
  2 in total

1.  N.m.r. and molecular-modelling studies of the solution conformation of heparin.

Authors:  B Mulloy; M J Forster; C Jones; D B Davies
Journal:  Biochem J       Date:  1993-08-01       Impact factor: 3.857

2.  A collaborative study of heparins from different sources.

Authors:  D R Bangham; P M Woodward
Journal:  Bull World Health Organ       Date:  1970       Impact factor: 9.408

  2 in total

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