Literature DB >> 13796012

The effect of nitrofurazone on Trypanosoma rhodesiense infections in mice.

J R BAKER.   

Abstract

Mice infected with a freshly isolated strain of Trypanosoma rhodesiense were not cured by ten daily intraperitoneal doses of 50, 100, 200, or 400 mg./kg. of nitrofurazone (5-nitrofurfuraldehyde semicarbazone). At the highest dosage used, the drug was lethal to some of the mice.

Entities:  

Keywords:  NITROFURANS/pharmacology; TRYPANOSOMIASIS/experimental

Mesh:

Substances:

Year:  1959        PMID: 13796012      PMCID: PMC1481731          DOI: 10.1111/j.1476-5381.1959.tb00267.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  3 in total

1.  Chemotherapy of Trypanosoma gambiense and Trypanosoma rhodesiense infections in guinea pigs with nitrofurazone.

Authors:  F EVENS; K NIEMEGEERS; A PACKCHANIAN
Journal:  Am J Trop Med Hyg       Date:  1957-07       Impact factor: 2.345

2.  Antibiotic lactones and synthetic analogs. III. Efficacy in experimental trypanosomiasis.

Authors:  N J GIARMAN
Journal:  J Pharmacol Exp Ther       Date:  1951-07       Impact factor: 4.030

3.  Chemotherapy of African sleeping sickness. I. Chemotherapy of experimental Trypanosoma gambiense infection in mice (Mus musculus) with nitrofurazone.

Authors:  A PACKCHANIAN
Journal:  Am J Trop Med Hyg       Date:  1955-07       Impact factor: 2.345

  3 in total

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