| Literature DB >> 1379434 |
Abstract
Nitric oxide (NO) has been identified recently as a multifunctional mediator, produced by, and acting on, most cells of the body. Besides its function as endothelium-derived relaxing factor, as a neurotransmitter and as an immune defence molecule, evidence is accumulating that NO participates in inflammatory- and autoimmune-mediated tissue destruction. Modulation of NO synthesis and action represents a new approach to the treatment of inflammatory and autoimmune conditions.Entities:
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Year: 1992 PMID: 1379434 DOI: 10.1016/0167-5699(92)90118-Q
Source DB: PubMed Journal: Immunol Today ISSN: 0167-5699