Literature DB >> 137935

HLA antigen studies in a family with C2 deficiency.

G Opelz, M M Glovsky.   

Abstract

Two children in a family were found to be homozygous for C2 deficiency; both parents and a third child were heterozygous. C2 deficiency was associated with the HLA haplotypes carrying the antigens B18 and DW2. Antigen A10 was absent in this family. Mixed lymphocyte culture studies among the family members confirmed the association of C2 deficiency with the HLA-D locus.

Entities:  

Mesh:

Substances:

Year:  1976        PMID: 137935     DOI: 10.1111/j.1744-313x.1976.tb00588.x

Source DB:  PubMed          Journal:  J Immunogenet        ISSN: 0305-1811


  6 in total

Review 1.  Lupus diseases associated with hereditary and acquired deficiencies of complement.

Authors:  V Agnello
Journal:  Springer Semin Immunopathol       Date:  1986

2.  Recurrent pyogenic infections in individuals with absence of the second component of complement.

Authors:  H A Sampson; A M Walchner; P J Baker
Journal:  J Clin Immunol       Date:  1982-01       Impact factor: 8.317

3.  Defective activation of the alternative pathway of complement in patients with homozygous C2 deficiency: studies in two unrelated families.

Authors:  R Schwertz; E Esser; R A Seger; A Rubinstein; G Hauptmann; V Wahn
Journal:  Eur J Pediatr       Date:  1991-07       Impact factor: 3.183

4.  HLA-linked C2 deficiency in a Dutch patient with systemic lupus erythematosus.

Authors:  L Berrens; H B de la Faille; E Borst-Eilers
Journal:  J Clin Pathol       Date:  1979-06       Impact factor: 3.411

5.  Renal transplantation in a patient with hereditary deficiency of the second component of complement.

Authors:  H J Zeitz; A Gewurz; O Jonasson; W P Geis; H Gewurz
Journal:  Clin Exp Immunol       Date:  1981-11       Impact factor: 4.330

6.  Association of low C2 and C4 serum levels with the HLA-DW2 allele in healthy individuals.

Authors:  C Nerl; H Grosse-Wilde; G Valet
Journal:  J Exp Med       Date:  1978-09-01       Impact factor: 14.307

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.