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Literature DB >> 13790097

Neuromuscular blockade by streptomycin and dihydrostreptomycin.

Abstract

Both streptomycin and dihydrostreptomycin in large doses produced neuromuscular blockade in different types of skeletal nerve-muscle preparations. Streptomycin had a quicker, more marked and a longer-lasting action than dihydrostreptomycin. Neostigmine reversed a partial block of streptomycin, but a complete neuromuscular block remained unaffected. Calcium ions antagonized the neuromuscular block of streptomycin rapidly but incompletely.

Entities: Chemical Disease

Keywords: MYONEURAL JUNCTION/pharmacology; STREPTOMYCIN/pharmacology; STREPTOMYCIN/related compounds

Mesh：

Substances：

Year: 1960 PMID： 13790097 PMCID： PMC1482259 DOI： 10.1111/j.1476-5381.1960.tb00271.x

Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826

4 in total

1. Neuromuscular-blocking action of streptomycin.

Authors: R E LODER; G F WALKER
Journal: Lancet Date: 1959-04-18 Impact factor: 79.321

2. Drug treatment of tuberculosis. I. Standard chemotherapy.

Authors: J CROFTON
Journal: Br Med J Date: 1960-07-30

3. The curariform action of streptomycin.

Authors: O V BRAZIL; A P CORRADO
Journal: J Pharmacol Exp Ther Date: 1957-08 Impact factor: 4.030

4. Neuro-muscular blockade by neomycin, potentiation by ether anesthesia and d-tubucurarine and antagonism by calcium and prostigmine.

Authors: A P CORRADO; A O RAMOS; C T DE ESCOBAR
Journal: Arch Int Pharmacodyn Ther Date: 1959-09-01

4 in total

3 in total

Neuromuscular blockade by streptomycin and dihydrostreptomycin.

1. Neuromuscular-blocking action of streptomycin.

2. Drug treatment of tuberculosis. I. Standard chemotherapy.

3. The curariform action of streptomycin.

4. Neuro-muscular blockade by neomycin, potentiation by ether anesthesia and d-tubucurarine and antagonism by calcium and prostigmine.

1. The pharmacology of pancuronium bromide (Org.NA97), a new potent steroidal neuromuscular blocking agent.

2. Glutamate inhibitory action of matrine at the crayfish neuromuscular junction.

3. Learning in a simple biological system: a pilot study of classical conditioning of human macrophages in vitro.