Literature DB >> 1378661

An 'anatomical cascade hypothesis' for Alzheimer's disease.

J Hardy1.   

Abstract

The molecular mechanisms of the cytopathology of Alzheimer's disease are very rapidly being elucidated. However, the factors that restrict the effects of this disease to specific neuroanatomical systems are less well understood. In this brief article a possible hypothesis is outlined to explain this apparent specific localization.

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Year:  1992        PMID： 1378661     DOI： 10.1016/0166-2236(92)90033-5

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  10 in total

1.  Assembly of α-synuclein aggregates on phospholipid bilayers.

Authors:  Zhengjian Lv; Mohtadin Hashemi; Siddhartha Banerjee; Karen Zagorski; Jean-Christophe Rochet; Yuri L Lyubchenko
Journal:  Biochim Biophys Acta Proteins Proteom       Date:  2019-06-19       Impact factor: 3.036

2.  In vivo characterization of the early states of the amyloid-beta network.

Authors:  Jorge Sepulcre; Mert R Sabuncu; Alex Becker; Reisa Sperling; Keith A Johnson
Journal:  Brain       Date:  2013-07       Impact factor: 13.501

3.  Treatment with D3 removes amyloid deposits, reduces inflammation, and improves cognition in aged AβPP/PS1 double transgenic mice.

Authors:  Thomas van Groen; Inga Kadish; Susanne Aileen Funke; Dirk Bartnik; Dieter Willbold
Journal:  J Alzheimers Dis       Date:  2013       Impact factor: 4.472

Review 4.  Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders.

Authors:  Mathias Jucker; Lary C Walker
Journal:  Ann Neurol       Date:  2011-10       Impact factor: 10.422

5.  Hippocampal tin, aluminum and zinc in Alzheimer's disease.

Authors:  F M Corrigan; G P Reynolds; N I Ward
Journal:  Biometals       Date:  1993       Impact factor: 2.949

6.  The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component.

Authors:  William E Klunk; Yanming Wang; Guo-feng Huang; Manik L Debnath; Daniel P Holt; Li Shao; Ronald L Hamilton; Milos D Ikonomovic; Steven T DeKosky; Chester A Mathis
Journal:  J Neurosci       Date:  2003-03-15       Impact factor: 6.167

7.  The Aβ oligomer eliminating D-enantiomeric peptide RD2 improves cognition without changing plaque pathology.

Authors:  Thomas van Groen; Sarah Schemmert; Oleksandr Brener; Lothar Gremer; Tamar Ziehm; Markus Tusche; Luitgard Nagel-Steger; Inga Kadish; Elena Schartmann; Anne Elfgen; Dagmar Jürgens; Antje Willuweit; Janine Kutzsche; Dieter Willbold
Journal:  Sci Rep       Date:  2017-11-24       Impact factor: 4.379

8.  A novel pathway for amyloids self-assembly in aggregates at nanomolar concentration mediated by the interaction with surfaces.

Authors:  Siddhartha Banerjee; Mohtadin Hashemi; Zhengjian Lv; Sibaprasad Maity; Jean-Christophe Rochet; Yuri L Lyubchenko
Journal:  Sci Rep       Date:  2017-03-30       Impact factor: 4.379

9.  Neurovascular coupling preserved in a chronic mouse model of Alzheimer's disease: Methodology is critical.

Authors:  Paul S Sharp; Kamar E Ameen-Ali; Luke Boorman; Sam Harris; Stephen Wharton; Clare Howarth; Osman Shabir; Peter Redgrave; Jason Berwick
Journal:  J Cereb Blood Flow Metab       Date:  2019-11-23       Impact factor: 6.200

10.  Stable cerebrospinal fluid neurogranin and β-site amyloid precursor protein cleaving enzyme 1 levels differentiate predementia Alzheimer's disease patients.

Authors:  Bjørn Eivind Kirsebom; Grit Richter; Kaja Nordengen; Dag Aarsland; Geir Bråthen; Betty M Tijms; Pieter Jelle Visser; Johanna Nilsson; Per Selnes; Milica G Kramberger; Bengt Winblad; Knut Waterloo; Berglind Gísladóttir; Kaj Blennow; Tormod Fladby
Journal:  Brain Commun       Date:  2022-09-24
  10 in total

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