Literature DB >> 137794

Sodium valproate in Huntington's chorea.

B K Tan, H J Leijnse-Ybema, M F Zee.   

Abstract

In a single-case study of Huntington's Chorea the effect of sodium valproate on motor behaviour was first compared with that of L-Dopa and than investigated further alone. Drug effect was assessed in terms of number of EMG-bursts with concurrent determinations of serum-levels of sodium valproate. The main result of this study was the development of a state of tolerance to sodium valproate.

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Year:  1976        PMID: 137794     DOI: 10.1016/s0303-8467(76)80007-8

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN: 0303-8467            Impact factor:   1.876


  4 in total

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3.  Dose-dependent improvement of myoclonic hyperkinesia due to Valproic acid in eight Huntington's Disease patients: a case series.

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Review 4.  Preclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned?

Authors:  Lisa Scheuing; Chi-Tso Chiu; Hsiao-Mei Liao; Gabriel R Linares; De-Maw Chuang
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  4 in total

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