Literature DB >> 1377645

Specific increase of a mitochondrial RNA transcript in chronic ethanol-fed rats.

J A Enríquez1, A Pérez-Martos, P Fernández-Silva, M J López-Pérez, J Montoya.   

Abstract

An in vitro transcription system utilizing isolated mitochondria has been used to study the effect of chronic ethanol consumption on liver mitochondrial DNA transcription. The results obtained showed an overall increase of RNA synthesis and a dramatic accumulation of a discrete polyadenylated RNA species. This effect is a consequence of the chronic ethanol consumption since these changes do not occur when isolated control mitochondria are incubated in the presence of ethanol.

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Year:  1992        PMID: 1377645     DOI: 10.1016/0014-5793(92)80639-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  2 in total

1.  Transient activation of mitochondrial translation regulates the expression of the mitochondrial genome during mammalian mitochondrial differentiation.

Authors:  L K Ostronoff; J M Izquierdo; J A Enríquez; J Montoya; J M Cuezva
Journal:  Biochem J       Date:  1996-05-15       Impact factor: 3.857

2.  Highly efficient DNA synthesis in isolated mitochondria from rat liver.

Authors:  J A Enríquez; J Ramos; A Pérez-Martos; M J López-Pérez; J Montoya
Journal:  Nucleic Acids Res       Date:  1994-05-25       Impact factor: 16.971

  2 in total

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