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Literature DB >> 13775772

Some effects of corticosteroids on the metabolism of histamine and 5-hydroxytryptamine in the rat.

Abstract

Daily intramuscular injections of cortisone, prednisolone, triamcinolone, fludrocortisone and 2-methylfludrocortisone reduced the histidine decarboxylase activity of the rat liver, but increased the enzyme activity of the pyloric stomach. Injections of histamine liberators or exposure to cold produced similar changes. After adrenalectomy, the histidine decarboxylase activities of the liver and pyloric stomach were unaltered, but the histaminase activity of the ileum was reduced. The 5-hydroxytryptophan decarboxylase activities of rat liver and kidney were not altered by treatment with corticosteroids.

Entities: Chemical Gene Species

Keywords: ADRENAL CORTEX HORMONES/pharmacology; HISTAMINE/metabolism; SEROTONIN/metabolism

Mesh：

Substances：

Year: 1961 PMID： 13775772 PMCID： PMC1482025 DOI： 10.1111/j.1476-5381.1961.tb01096.x

Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826

14 in total

4. Histamine and 5-hydroxytryptamine in the intestinal tract of germ-free animals, animals harbouring one microbial species and conventional animals.

Authors: M H BEAVER; B S WOSTMANN
Journal: Br J Pharmacol Chemother Date: 1962-12

5. THE FORMATION OF (14C)-HISTAMINE IN VIVO IN NORMAL RATS AND IN RATS TREATED WITH LIOTHYRONINE.

Authors: T BJURO; H WESTLING; H WETTERQVIST
Journal: Br J Pharmacol Chemother Date: 1964-12

6. THE EFFECT OF SODIUM INTAKE ON THE URINARY HISTAMINE IN ADRENALECTOMIZED RATS.

Authors: T BJUROE; H WESTLING
Journal: Br J Pharmacol Chemother Date: 1964-06

6 in total

Some effects of corticosteroids on the metabolism of histamine and 5-hydroxytryptamine in the rat.

1. Further studies on the biosynthesis of 5-hydroxytryptamine.

2. The formation of histamine in the rat foetus.

3. Release of 5-hydroxytryptamine and histamine from tissues of the rat.

4. 5-Hydroxytryptamine and tissue mast cells.

5. Histidine decarboxylase of rat stomach and other mammalian tissues.

6. Adrenalectomy and tissue amines.

7. Adrenal cortical hormones and the formation of histamine and 5-hydroxytryptamine.

8. Preliminary studies on the biosynthesis of 5-hydroxytryptamine.

9. Studies on mammalian histidine decarboxylase.

10. Relationship of stress-induced histidine decarboxylase to circulatory homeostasis and shock.

1. Inhibition by glucocorticoids of the mast cell-dependent weal and flare response in human skin in vivo.

2. [Histamine content in postmortal experimental burn injuries (author's transl)].

3. Some effects of corticosteroids on tissue histamine levels in the guinea-pig.

4. Histamine and 5-hydroxytryptamine in the intestinal tract of germ-free animals, animals harbouring one microbial species and conventional animals.

5. THE FORMATION OF (14C)-HISTAMINE IN VIVO IN NORMAL RATS AND IN RATS TREATED WITH LIOTHYRONINE.

6. THE EFFECT OF SODIUM INTAKE ON THE URINARY HISTAMINE IN ADRENALECTOMIZED RATS.