Literature DB >> 1376697

Bleomycin-detectable iron in the plasma of premature and full-term neonates.

P J Evans1, R Evans, I Z Kovar, A F Holton, B Halliwell.   

Abstract

The bleomycin assay measures non-transferrin-bound iron, able to catalyze free radical reactions, in human plasma. No bleomycin-detectable iron is present in plasma from healthy adults. However, plasma from 3/15 premature babies was positive in this assay. Plasma from 52 apparently-healthy term babies was analyzed and 11 were positive in the bleomycin assay. Hence not only some premature but also some full-term apparently-healthy babies may be at risk of severe oxidative damage.

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Year:  1992        PMID: 1376697     DOI: 10.1016/0014-5793(92)80521-h

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  13 in total

1.  Effect of blood transfusions on oxidative stress in preterm infants.

Authors:  C Dani; E Martelli; G Bertini; M Pezzati; M Rossetti; G Buonocore; P Paffetti; F F Rubaltelli
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2004-09       Impact factor: 5.747

2.  Blood transfusion increases radical promoting non-transferrin bound iron in preterm infants.

Authors:  K Hirano; T Morinobu; H Kim; M Hiroi; R Ban; S Ogawa; H Ogihara; H Tamai; T Ogihara
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2001-05       Impact factor: 5.747

Review 3.  Determinants of antioxidant status in humans.

Authors:  A M Papas
Journal:  Lipids       Date:  1996-03       Impact factor: 1.880

4.  Vitamin C supplementation in very preterm infants: a randomised controlled trial.

Authors:  B A Darlow; H Buss; F McGill; L Fletcher; P Graham; C C Winterbourn
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  2005-03       Impact factor: 5.747

5.  On the source of the non-transferrin-bound iron which accumulates in packed red blood cell units during storage.

Authors:  Keit J Collard; Desley L White
Journal:  Blood Transfus       Date:  2014-06-05       Impact factor: 3.443

Review 6.  Transfusion related morbidity in premature babies: Possible mechanisms and implications for practice.

Authors:  Keith James Collard
Journal:  World J Clin Pediatr       Date:  2014-08-08

7.  Pro- or antioxidant activity of vitamin C in preterm infants?

Authors:  T M Berger; B Frei
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1995-05       Impact factor: 5.747

8.  Influence of iron status on risk of maternal or neonatal infection and on neonatal mortality with an emphasis on developing countries.

Authors:  Loretta Brabin; Bernard J Brabin; Sabine Gies
Journal:  Nutr Rev       Date:  2013-06-06       Impact factor: 7.110

Review 9.  Non transferrin bound iron: nature, manifestations and analytical approaches for estimation.

Authors:  Meghna Patel; D V S S Ramavataram
Journal:  Indian J Clin Biochem       Date:  2012-08-31

10.  Transient iron overload with bleomycin detectable iron in the plasma of patients with adult respiratory distress syndrome.

Authors:  J M Gutteridge; G J Quinlan; T W Evans
Journal:  Thorax       Date:  1994-07       Impact factor: 9.139

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