Literature DB >> 1376671

Demonstration of mismatch negativity in the monkey.

D C Javitt1, C E Schroeder, M Steinschneider, J C Arezzo, H G Vaughan.   

Abstract

In humans, deviant auditory stimuli elicit an event-related potential (ERP) component, termed "mismatch negativity" (MMN), that reflects the operation of a cortical detector of infrequent stimulus change. Epidural auditory ERPs were recorded from 3 cynomolgous monkeys in response to soft and loud clicks. "Oddball" loud or soft stimuli elicited a long-duration frontocentral negativity, peaking at approximately 85 msec, that was superimposed upon cortically generated obligatory ERP components. These data suggest that monkeys might serve as a heuristically valuable system in which to study the neurochemical and neuroanatomical substrates of early context-dependent ERP generation.

Entities:  

Mesh：

Year:  1992        PMID： 1376671     DOI： 10.1016/0013-4694(92)90137-7

Source DB:  PubMed          Journal:  Electroencephalogr Clin Neurophysiol        ISSN： 0013-4694


  41 in total

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