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Literature DB >> 13762785

Studies on primary atypical pneumonia. III. A factor in normal serum which enhances the reaction between PAP virus and convalescent serum.

Abstract

A factor present in fresh normal human or guinea pig serum enhances the primary atypical pneumonia (PAP) antibody titers in serological reaction with its homologous virus as tested by indirect fluorescent antibody staining. This factor is not properdin. It has many properties similar to complement but may not be identical with complement. The addition of this enhancement factor to human sera convalescent from primary atypical pneumonia has made the serological test more sensitive without affecting its specificity.

Entities: Disease Species

Keywords: PNEUMONIA, PRIMARY ATYPICAL/virology

Mesh：

Substances：

Year: 1961 PMID： 13762785 PMCID： PMC2137341 DOI： 10.1084/jem.113.1.111

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

10 in total

1. Measurement of the components of complement by the reagent titration technique.

Authors: R J WEDGWOOD
Journal: Z Immun exp ther Date: 1959 Oct-Nov

2. A fluorescent antibody study of the simian foamy agent.

Authors: T R CARSKI
Journal: J Immunol Date: 1960-04 Impact factor: 5.422

3. Staining of complement and modification of fluorescent antibody procedures.

Authors: R A GOLDWASSER; C C SHEPARD
Journal: J Immunol Date: 1958-02 Impact factor: 5.422

4. Studies on the role of Ca++ and Mg++ in complement fixation and immune hemolysis. I. Uptake of complement nitrogen by specific precipitates and its inhibition by ethylenediamine tetraacetate.

Authors: L LEVINE; K M COWAN; A G OSLER; M M MAYER
Journal: J Immunol Date: 1953-11 Impact factor: 5.422

5. Diagnostic complement fixation. I. A method.

Authors: A G OSLER; J H STRAUSS; M M MAYER
Journal: Am J Syph Gonorrhea Vener Dis Date: 1952-03

6. The dengue group of viruses and its family relationships.

Authors: A B SABIN
Journal: Bacteriol Rev Date: 1950-09

7. The properdin system and immunity. V. The bactericidal activity of the properdin system.

Authors: A C WARDLAW; L PILLEMER
Journal: J Exp Med Date: 1956-05-01 Impact factor: 14.307

8. The properdin system and immunity. VI. The inactivation of Newcastle disease virus by the properdin system.

Authors: H S GINSBERG; L PILLEMER; R J WEDGWOOD
Journal: J Exp Med Date: 1956-11-01 Impact factor: 14.307

9. Studies on primary atypical pneumonia. II. Observations concerning the development and immunological characteristics of antibody in patients.

Authors: C LIU; M D EATON; J T HEYL
Journal: J Exp Med Date: 1959-06-01 Impact factor: 14.307

10. STUDIES ON THE ETIOLOGY OF PRIMARY ATYPICAL PNEUMONIA : A FILTERABLE AGENT TRANSMISSIBLE TO COTTON RATS, HAMSTERS, AND CHICK EMBRYOS.

Authors: M D Eaton; G Meiklejohn; W van Herick
Journal: J Exp Med Date: 1944-06-01 Impact factor: 14.307

10 in total

8 in total

1. DIRECT AND INDIRECT FLUORESCENT-ANTIBODY TECHNIQUES FOR THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM-TRACHOMA GROUP OF AGENTS.

Authors: M R ROSS; E K BORMAN
Journal: J Bacteriol Date: 1963-04 Impact factor: 3.490

Review 2. MYCOPLASMA SPECIES OF MAN.

Authors: L HAYFLICK; R M CHANOCK
Journal: Bacteriol Rev Date: 1965-06

Studies on primary atypical pneumonia. III. A factor in normal serum which enhances the reaction between PAP virus and convalescent serum.

1. Measurement of the components of complement by the reagent titration technique.

2. A fluorescent antibody study of the simian foamy agent.

3. Staining of complement and modification of fluorescent antibody procedures.

4. Studies on the role of Ca++ and Mg++ in complement fixation and immune hemolysis. I. Uptake of complement nitrogen by specific precipitates and its inhibition by ethylenediamine tetraacetate.

5. Diagnostic complement fixation. I. A method.

6. The dengue group of viruses and its family relationships.

7. The properdin system and immunity. V. The bactericidal activity of the properdin system.

8. The properdin system and immunity. VI. The inactivation of Newcastle disease virus by the properdin system.

9. Studies on primary atypical pneumonia. II. Observations concerning the development and immunological characteristics of antibody in patients.

10. STUDIES ON THE ETIOLOGY OF PRIMARY ATYPICAL PNEUMONIA : A FILTERABLE AGENT TRANSMISSIBLE TO COTTON RATS, HAMSTERS, AND CHICK EMBRYOS.

1. DIRECT AND INDIRECT FLUORESCENT-ANTIBODY TECHNIQUES FOR THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM-TRACHOMA GROUP OF AGENTS.

Review 2. MYCOPLASMA SPECIES OF MAN.

3. Fluorescent-stainable antibodies to the Eaton agent in human primary atypical pneumonia transmission studies.

4. Assay of rubella antibodies by immunofluorescence, complement fixation and neutralization.

5. Cold agglutinin anti-I and Mycoplasma pneumoniae.

6. CYTOPATHIC EFFECT OF THE ATYPICAL PNEUMONIA ORGANISM IN CULTURES OF HUMAN TISSUE.

7. Isolation and characterization of fractions of Mycoplasma pneumoniae. II. Antigenicity and immunogenicity.

8. Hog cholera IV. Detection of the virus in tissue culture preparations by the fluorescent antibody technique.