Literature DB >> 1375529

X-linked gene MIC5 codes for the L1 adhesion molecule recognized by monoclonal antibody R1.

K Patel1, G Banting, G Frost, J T Kemshead.   

Abstract

Monoclonal antibody (MoAb) R1 was generated by use of human-mouse hybrids containing only the long arm of chromosome X as the human component. It recognizes plasma membrane glycoproteins of 145 and 200 kd as well as a soluble protein of 195 kd. In this study, using a biochemical approach, we identified these glycoproteins as the human L1 adhesion molecule.

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Year:  1992        PMID: 1375529     DOI: 10.1016/0165-4608(92)90226-x

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  1 in total

1.  Enhanced L1CAM expression on pancreatic tumor endothelium mediates selective tumor cell transmigration.

Authors:  Yasmin Issa; Daniel Nummer; Tobias Seibel; Susanne Sebens Müerköster; Moritz Koch; Friedrich-Hubertus Schmitz-Winnenthal; Luis Galindo; Juergen Weitz; Philipp Beckhove; Peter Altevogt
Journal:  J Mol Med (Berl)       Date:  2008-10-18       Impact factor: 4.599

  1 in total

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