| Literature DB >> 1375026 |
B Sommer1, H Monyer, W Wisden, T A Verdoorn, N Burnashev, R Sprengel, B Sakmann, P H Seeburg.
Abstract
L-glutamate is the major excitatory neurotransmitter in the vertebrate central nervous system. Most cells are responsive to glutamate which activates cation channels with different pharmacological, kinetic, and ion permeability properties. These channels play important roles in neurotransmission, memory acquisition as well as acute and chronic disorders of the brain. The present report summarizes recent knowledge on AMPA (a-amino-3-hydroxy-5-methyl-isoxazole-4-propionic acid) receptors which mediate fast synaptic neurotransmission.Entities:
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Year: 1992 PMID： 1375026
Source DB: PubMed Journal: Arzneimittelforschung ISSN： 0004-4172