Literature DB >> 1374902

Modulation of L-type calcium channels by sodium ions.

C W Balke1, W G Wier.   

Abstract

It is universally believed that the removal of external sodium ions is without effect on calcium current. We now report that in enzymatically isolated guinea pig ventricular cells, the replacement of external sodium ions with certain other cations causes a 3- to 6-fold increase in peak L-type calcium current. The increase in current is reversibly blocked by L-type calcium-channel antagonists, not mediated by changes in internal calcium, and is inhibited by intracellular 5'-adenylyl imidodiphosphate, a nonhydrolyzable ATP analogue. The effects of sodium removal (and isoproterenol) were almost completely blocked by intracellular application of a specific (peptide) inhibitor of cAMP-dependent protein kinase. These experiments demonstrate a previously unknown effect of sodium ions to modulate calcium-channel phosphorylation via cAMP-dependent protein kinase.

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Year:  1992        PMID： 1374902      PMCID： PMC49093          DOI： 10.1073/pnas.89.10.4417

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  39 in total

Review 1.  Regulation of cardiac L-type calcium current by phosphorylation and G proteins.

Authors:  W Trautwein; J Hescheler
Journal:  Annu Rev Physiol       Date:  1990       Impact factor: 19.318

2.  Calcium diffusion modeling in a spherical neuron. Relevance of buffering properties.

Authors:  F Sala; A Hernández-Cruz
Journal:  Biophys J       Date:  1990-02       Impact factor: 4.033

3.  Molecular model for receptor-stimulated calcium spiking.

Authors:  T Meyer; L Stryer
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

4.  Sodium/calcium exchange in mammalian ventricular muscle: a study with sodium-sensitive micro-electrodes.

Authors:  R A Chapman; A Coray; J A McGuigan
Journal:  J Physiol       Date:  1983-10       Impact factor: 5.182

5.  On the mechanism of beta-adrenergic regulation of the Ca channel in the guinea-pig heart.

Authors:  M Kameyama; F Hofmann; W Trautwein
Journal:  Pflugers Arch       Date:  1985-10       Impact factor: 3.657

6.  Calcium current restitution in mammalian ventricular myocytes is modulated by intracellular calcium.

Authors:  G N Tseng
Journal:  Circ Res       Date:  1988-08       Impact factor: 17.367

7.  Adrenoceptor-mediated changes of excitation and contraction in ventricular heart muscle from guinea-pigs and rabbits.

Authors:  J Hescheler; H Nawrath; M Tang; W Trautwein
Journal:  J Physiol       Date:  1988-03       Impact factor: 5.182

8.  Ryanodine does not affect calcium current in guinea pig ventricular myocytes in which Ca2+ is buffered.

Authors:  C W Balke; W G Wier
Journal:  Circ Res       Date:  1991-03       Impact factor: 17.367

9.  Calcium channel selectivity for divalent and monovalent cations. Voltage and concentration dependence of single channel current in ventricular heart cells.

Authors:  P Hess; J B Lansman; R W Tsien
Journal:  J Gen Physiol       Date:  1986-09       Impact factor: 4.086

10.  Two kinds of calcium channels in canine atrial cells. Differences in kinetics, selectivity, and pharmacology.

Authors:  B P Bean
Journal:  J Gen Physiol       Date:  1985-07       Impact factor: 4.086
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  11 in total

1.  Regulation of calcium channel expression in neonatal myocytes by catecholamines.

Authors:  T Maki; E J Gruver; A J Davidoff; N Izzo; D Toupin; W Colucci; A R Marks; J D Marsh
Journal:  J Clin Invest       Date:  1996-02-01       Impact factor: 14.808

2.  Regulation of Ca channel by intracellular Ca2+ and Mg2+ in frog ventricular cells.

Authors:  K Yamaoka; I Seyama
Journal:  Pflugers Arch       Date:  1996-01       Impact factor: 3.657

3.  Local, stochastic release of Ca2+ in voltage-clamped rat heart cells: visualization with confocal microscopy.

Authors:  J R López-López; P S Shacklock; C W Balke; W G Wier
Journal:  J Physiol       Date:  1994-10-01       Impact factor: 5.182

4.  The P2Z-purinoceptor of human lymphocytes: actions of nucleotide agonists and irreversible inhibition by oxidized ATP.

Authors:  J S Wiley; J R Chen; M B Snook; G P Jamieson
Journal:  Br J Pharmacol       Date:  1994-07       Impact factor: 8.739

5.  Disruption of actin filaments increases the activity of sodium-conducting channels in human myeloid leukemia cells.

Authors:  Y A Negulyaev; E A Vedernikova; A V Maximov
Journal:  Mol Biol Cell       Date:  1996-12       Impact factor: 4.138

6.  I(Ca(TTX)) channels are distinct from those generating the classical cardiac Na(+) current.

Authors:  Y Chen-Izu; Q Sha; S R Shorofsky; S W Robinson; W G Wier; L Goldman; C W Balke
Journal:  Biophys J       Date:  2001-11       Impact factor: 4.033

7.  Sodium-selective channels in membranes of rat macrophages.

Authors:  Y A Negulyaev; E A Vedernikova
Journal:  J Membr Biol       Date:  1994-02       Impact factor: 1.843

8.  Stimulation of protein phosphatases as a mechanism of the muscarinic-receptor-mediated inhibition of cardiac L-type Ca2+ channels.

Authors:  S Herzig; A Meier; M Pfeiffer; J Neumann
Journal:  Pflugers Arch       Date:  1995-02       Impact factor: 3.657

9.  An antisense oligonucleotide against H1 inhibits the classical sodium current but not ICa(TTX) in rat ventricular cells.

Authors:  Qun Sha; Shawn W Robinson; Stacey L McCulle; Stephen R Shorofsky; Paul A Welling; L Goldman; C William Balke
Journal:  J Physiol       Date:  2003-01-24       Impact factor: 5.182

10.  The Ca2+ transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations.

Authors:  Colin M Rees; Jun-Hai Yang; Marc Santolini; Aldons J Lusis; James N Weiss; Alain Karma
Journal:  Elife       Date:  2018-09-25       Impact factor: 8.140
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