Literature DB >> 1374814

Differential human immunodeficiency virus expression in CD4+ cloned lymphocytes: from viral latency to replication.

A Chapel1, A Bensussan, E Vilmer, D Dormont.   

Abstract

By using cloning methodology, 13 CD4+, CD8-, CD45RO+, and CD29+ clones, isolated from human immunodeficiency virus (HIV)-negative donors, have been characterized and tested regarding their susceptibility to two strains of HIV type 1 (HIV-1). Infected clones possess integrated provirus. Only six are able to replicate HIV-1, while seven may normally grow without cytopathic effect and without viral replication. These results argue that all CD4+ lymphocyte clones may be infectable but that a heterogeneity exists regarding their abilities to replicate HIV-1.

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Year:  1992        PMID： 1374814      PMCID： PMC241191     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  22 in total

1.  Characterization of cellular proteins recognizing the HIV enhancer using a microscale DNA-affinity precipitation assay.

Authors:  B R Franza; S F Josephs; M Z Gilman; W Ryan; B Clarkson
Journal:  Nature       Date:  1987 Nov 26-Dec 2       Impact factor: 49.962

2.  Identification of HIV-infected seronegative individuals by a direct diagnostic test based on hybridisation to amplified viral DNA.

Authors:  M Loche; B Mach
Journal:  Lancet       Date:  1988-08-20       Impact factor: 79.321

3.  Cell-specific activity of the human immunodeficiency virus enhancer repeat in vitro.

Authors:  H Lubon; P Ghazal; J A Nelson; L Hennighausen
Journal:  AIDS Res Hum Retroviruses       Date:  1988-10       Impact factor: 2.205

4.  DNA amplification for direct detection of HIV-1 in DNA of peripheral blood mononuclear cells.

Authors:  C Y Ou; S Kwok; S W Mitchell; D H Mack; J J Sninsky; J W Krebs; P Feorino; D Warfield; G Schochetman
Journal:  Science       Date:  1988-01-15       Impact factor: 47.728

5.  Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase.

Authors:  R K Saiki; D H Gelfand; S Stoffel; S J Scharf; R Higuchi; G T Horn; K B Mullis; H A Erlich
Journal:  Science       Date:  1988-01-29       Impact factor: 47.728

6.  Isolation of HIV in a seronegative demented patient without symptoms of immune deficiency.

Authors:  F Boussin; D Dormont; B Spire; H Fleury; F Rey; D Bequet; J Goasguen; P Brunet
Journal:  Cancer Detect Prev       Date:  1988

7.  Prominent expansion of circulating lymphocytes bearing gamma T-cell receptors, with preferential expression of variable gamma genes after allogeneic bone marrow transplantation.

Authors:  E Vilmer; F Triebel; V David; C Rabian; M Schumpp; G Leca; L Degos; T Hercend; F Sigaux; A Bensussan
Journal:  Blood       Date:  1988-09       Impact factor: 22.113

8.  T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV.

Authors:  D Klatzmann; E Champagne; S Chamaret; J Gruest; D Guetard; T Hercend; J C Gluckman; L Montagnier
Journal:  Nature       Date:  1984 Dec 20-1985 Jan 2       Impact factor: 49.962

9.  Integrated proviral human immunodeficiency virus type 1 is present in CD4+ peripheral blood lymphocytes in healthy seropositive individuals.

Authors:  M C Psallidopoulos; S M Schnittman; L M Thompson; M Baseler; A S Fauci; H C Lane; N P Salzman
Journal:  J Virol       Date:  1989-11       Impact factor: 5.103

10.  Characterization of the RNA dependent DNA polymerase of a new human T-lymphotropic retrovirus (lymphadenopathy associated virus).

Authors:  M A Rey; B Spire; D Dormont; F Barre-Sinoussi; L Montagnier; J C Chermann
Journal:  Biochem Biophys Res Commun       Date:  1984-05-31       Impact factor: 3.575
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  4 in total

1.  Analysis of long-term viral expression in CEM cells persistently infected with non syncytium-inducing HIV-1 strains.

Authors:  J Yelle; R Morisset; L Thibodeau
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574

Review 2.  The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection.

Authors:  S Bour; R Geleziunas; M A Wainberg
Journal:  Microbiol Rev       Date:  1995-03

Review 3.  Pathogenesis of human immunodeficiency virus infection.

Authors:  J A Levy
Journal:  Microbiol Rev       Date:  1993-03

4.  Two subpopulations of human triple-negative thymic cells are susceptible to infection by human immunodeficiency virus type 1 in vitro.

Authors:  H Valentin; M T Nugeyre; F Vuillier; L Boumsell; M Schmid; F Barré-Sinoussi; R A Pereira
Journal:  J Virol       Date:  1994-05       Impact factor: 5.103
  4 in total

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