| Literature DB >> 1374500 |
M Sessa1, R Nemni, S Iannaccone, A Quattrini, V Confalonieri, N Canal.
Abstract
We treated adult mice with human recombinant interleukin-2 (IL-2) and determined the expression of the genes encoding for the major central and peripheral myelin proteins. In the CNS, myelin basic protein (MBP) and myelin-associated glycoprotein (MAG) mRNA levels were the same both in IL-2-treated and in control mice. Proteolipid protein (PLP) transcript was decreased in IL-2-treated animals when compared to controls. In the PNS, the messages for the glycoprotein P0 and for MBP were markedly increased in IL-2-treated animals when compared to controls.Entities:
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Year: 1992 PMID： 1374500 DOI： 10.1016/0169-328x(92)90135-x
Source DB: PubMed Journal: Brain Res Mol Brain Res ISSN： 0169-328X