Literature DB >> 13743877

Radioprotection by mitotic inhibitors and mercaptoethylamine.

W E ROTHE, M M GRENAN.   

Abstract

In the mouse, chemical interference with cellular proliferation alters the radiosensitivity of the bone marrow, and this results in protection from otherwise lethal x-irradiation. When intestinal damage is minimized by appropriate timing and dosage, many mitotic inhibitors increase radioresistance and enhance the protective effects of mercaptoethylamine.

Entities:  

Keywords:  CELL DIVISION/pharmacology; MERCAPTOETHYLAMINES/pharmacology; RADIATION PROTECTION/experimental

Mesh：

Substances：

Year:  1961        PMID： 13743877     DOI： 10.1126/science.133.3456.888

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  3 in total

1.  The influence of thymine and 5-bromouracil on the sensitivity of Escherichia coli to alkylation, UV and x-irradiation.

Authors:  V Fucík; S Zadrazil; Z Sormová
Journal:  Folia Microbiol (Praha)       Date:  1966       Impact factor: 2.099

2.  Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition.

Authors:  Søren M Johnson; Chad D Torrice; Jessica F Bell; Kimberly B Monahan; Qi Jiang; Yong Wang; Matthew R Ramsey; Jian Jin; Kwok-Kin Wong; Lishan Su; Daohong Zhou; Norman E Sharpless
Journal:  J Clin Invest       Date:  2010-06-23       Impact factor: 14.808

3.  Cabazitaxel-induced stabilization of microtubules enhances radiosensitivity in ovarian cancer cells.

Authors:  Charles A Kunos; Tammy Stefan; James W Jacobberger
Journal:  Front Oncol       Date:  2013-09-18       Impact factor: 6.244
  3 in total

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