Immunohistochemical evaluation of oral myxoid lesions.

Oral examples of neurothekeomas (nerve sheath myxomas), soft tissue myxomas, and focal mucinous and odontogenic myxomas were examined for selected markers. With the use of avidin-biotin complex staining procedures, these specimens of lesions were stained with antibodies to S-100 protein, neurospecific enolase, neurofilaments, desmin, and vimentin. Our results show that the use of immunohistochemical markers for these neural antigens can aid in distinguishing nerve sheath myxomas from other oral myxoid lesions.