| Literature DB >> 13738006 |
R E PRIEST, R M KOPLITZ, E P BENDITT.
Abstract
Estradiol in large amounts reduces the incorporation of radioactive sulfate into cartilage and aortas of rats. This reduction becomes apparent within 3 days for cartilage and 3 weeks for aorta. The effect is not mediated through suppression of testosterone secretion and the hypophysis is not necessary for the effect to be demonstrated. The thoracic segment of aortas from normal rats incorporates more sulfate than does the abdominal segment and this difference is reduced following the administration of estradiol.Entities:
Keywords: AORTA/metabolism; CARTILAGE/metabolism; ESTRADIOL/pharmacology; SULFATES/metabolism
Mesh:
Substances:
Year: 1960 PMID: 13738006 PMCID: PMC2137206 DOI: 10.1084/jem.112.1.225
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307