Literature DB >> 13736101

Folic acid and other absorption tests in lymphosarcoma, chronic lymphocytic leukaemia, and some related conditions.

W R PITNEY, R A JOSKE, N L MACKINNON.   

Abstract

An improved folic acid absorption test is described in detail. Using the folic acid and other absorption tests, a study of intestinal function has been made in eight patients with lymphosarcoma, eight with chronic lymphocytic leukaemia, two with Hodgkin's disease, and one each with reticulum cell sarcoma, Whipple's disease, and macroglobulinaemia. It was found that laboratory evidence of intestinal malabsorption was extremely common in patients with this group of diseases. The folic acid absorption test was the most sensitive single index of malabsorption of the tests used in this study. Correlation between the different absorption tests was poor, and there does not appear to be a characteristic biochemical profile of intestinal function in these patients.

Entities:  

Keywords:  FOLIC ACID/metabolism; INTESTINES/pathology; LEUKEMIA, LYMPHOCYTIC/complications; LYMPHOSARCOMA/complications

Mesh:

Substances:

Year:  1960        PMID: 13736101      PMCID: PMC480114          DOI: 10.1136/jcp.13.5.440

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  11 in total

1.  The clearance from the plasma of folic acid injected intravenously in normal subjects and patients with megaloblastic anaemia.

Authors:  I CHANARIN; D L MOLLIN; B B ANDERSON
Journal:  Br J Haematol       Date:  1958-10       Impact factor: 6.998

2.  Effect of prednisolone on anaemia associated with macroglobulinemia.

Authors:  W R PITNEY; W J O'SULLIVAN; J A OWEN
Journal:  Br Med J       Date:  1958-12-20

3.  The d-xylose absorption test in malabsorption syndromes.

Authors:  J A BENSON; P J CULVER; S RAGLAND; C M JONES; G D DRUMMEY; E BOUGAS
Journal:  N Engl J Med       Date:  1957-02-21       Impact factor: 91.245

4.  The absorption of folic acid.

Authors:  I CHANARIN; B B ANDERSON; D L MOLLIN
Journal:  Br J Haematol       Date:  1958-04       Impact factor: 6.998

5.  Diagnostic value of radioactive vitamin B12.

Authors:  W R PITNEY; J B STOKES
Journal:  Australas Ann Med       Date:  1958-05

6.  Lymphoma of the stomach and intestine.

Authors:  J F SKRIMSHIRE
Journal:  Q J Med       Date:  1955-07

7.  The sprue syndrome secondary to lymphoma of the small bowel.

Authors:  M H SLEISENGER; T P ALMY; D P BARR
Journal:  Am J Med       Date:  1953-11       Impact factor: 4.965

8.  The occurrence of growth factors for Lactobacillus leichmannii; Streptococcus faecalis and Leuconostoc citrovorum in the tissues of pernicious anaemia patients and controls.

Authors:  R H GIRDWOOD
Journal:  Biochem J       Date:  1952-09       Impact factor: 3.857

9.  Clinical and Biochemical Syndrome in Lymphadenoma.

Authors:  N H Fairley; F P Mackie
Journal:  Br Med J       Date:  1937-02-20

10.  The concentration of folic acid in leukocytes; observations on normal subjects and persons with leukemia.

Authors:  M E SWENDSEID; F H BETHELL; O D BIRD
Journal:  Cancer Res       Date:  1951-11       Impact factor: 12.701

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  10 in total

1.  Megaloblastic erythropoiesis in multiple myeloma.

Authors:  J FORSHAW
Journal:  Br Med J       Date:  1963-07-13

2.  Absorption of folic acid and D-xylose as tests of small-intestinal function.

Authors:  I CHANARIN; M C BENNETT
Journal:  Br Med J       Date:  1962-04-07

3.  Immunogold-silver technique applied to showing malignant B cell infiltration of gastrointestinal tract in patients with chronic lymphocytic leukaemia and non-Hodgkin's lymphoma.

Authors:  G Smith; J Crocker; P Nar; I Chesner; M J Leyland
Journal:  J Clin Pathol       Date:  1987-07       Impact factor: 3.411

4.  Chronic lymphocytic leukemia.

Authors:  D W Martin; R C Siegel; L H Smith
Journal:  West J Med       Date:  1977-09

5.  Small intestinal bacterial overgrowth in patients with chronic lymphocytic leukaemia.

Authors:  G M Smith; I M Chesner; P Asquith; M J Leyland
Journal:  J Clin Pathol       Date:  1990-01       Impact factor: 3.411

6.  Intestinal structure and function in neoplastic disease.

Authors:  F A Klipstein; G Smarth
Journal:  Am J Dig Dis       Date:  1969-12

7.  Folate deficiency secondary to disease of the intestinal tract.

Authors:  F A Klipstein
Journal:  Bull N Y Acad Med       Date:  1966-08

8.  Folic acid deficiency in leukemia and lymphomas.

Authors:  D P Rose
Journal:  J Clin Pathol       Date:  1966-01       Impact factor: 3.411

9.  A study of folate absorption and metabolism in man utilizing carbon-14--labeled polyglutamates synthesized by the solid phase method.

Authors:  C E Butterworth; C M Baugh; C Krumdieck
Journal:  J Clin Invest       Date:  1969-06       Impact factor: 14.808

10.  Folates in megaloblastic anaemia.

Authors:  J METZ
Journal:  Bull World Health Organ       Date:  1963       Impact factor: 9.408

  10 in total

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