Literature DB >> 1373607

Stem cell factor has histamine releasing activity in rat connective tissue-type mast cells.

K Nakajima1, K Hirai, M Yamaguchi, T Takaishi, K Ohta, Y Morita, K Ito.   

Abstract

Stem cell factor (SCF) was documented to be involved in the growth of mast cells controlled by fibroblasts. We tested the effect of recombinant rat SCF on degranulation from rat peritoneal mast cells (connective tissue-type mast cells: CTMC). SCF induced histamine release (approximately 20% of total histamine content) in a dose-dependent fashion. The release response was relatively rapid and reached a maximum within 5 min. The release showed total dependence on the presence of extracellular phosphatidylserine (PTS). These results reveal that SCF has histamine releasing activity in CTMC.

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Year:  1992        PMID： 1373607     DOI： 10.1016/s0006-291x(05)80300-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  9 in total

Review 1.  Mast cells. Receptors, secretagogues, and signaling.

Authors:  Bhavya B Sharma; John R Apgar; Fu-Tong Liu
Journal:  Clin Rev Allergy Immunol       Date:  2002-04       Impact factor: 8.667

2.  Novel protective effects of stem cell factor in a murine model of acute septic peritonitis. Dependence on MCP-1.

Authors:  C L Bone-Larson; C M Hogaboam; M L Steinhauser; S H Oliveira; N W Lukacs; R M Strieter; S L Kunkel
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

3.  Stem cell factor enhances immunoglobulin E-dependent mediator release from cultured rat bone marrow-derived mast cells: activation of previously unresponsive cells demonstrated by a novel ELISPOT assay.

Authors:  P B Hill; A J MacDonald; E M Thornton; G F Newlands; S J Galli; H R Miller
Journal:  Immunology       Date:  1996-02       Impact factor: 7.397

4.  Epidermal stem cell factor augments the inflammatory response in irritant and allergic contact dermatitis.

Authors:  Eric L Carter; Sean O'Herrin; Carla Woolery; B Jack Longley
Journal:  J Invest Dermatol       Date:  2008-01-17       Impact factor: 8.551

5.  Characterization of purification-associated reduction in IgE-dependent histamine release from rat peritoneal mast cells.

Authors:  N Inagaki; H Kawasaki; H Nagai
Journal:  Inflamm Res       Date:  1995-12       Impact factor: 4.575

6.  Stem cell factor-induced airway hyperreactivity in allergic and normal mice.

Authors:  E Campbell; C Hogaboam; P Lincoln; N W Lukacs
Journal:  Am J Pathol       Date:  1999-04       Impact factor: 4.307

7.  Stem cell factor potentiates histamine secretion by multiple mechanisms, but does not affect tumour necrosis factor-alpha release from rat mast cells.

Authors:  T J Lin; E Y Bissonnette; A Hirsh; A D Befus
Journal:  Immunology       Date:  1996-10       Impact factor: 7.397

8.  Stem-cell factor, the kit ligand, induces direct degranulation of rat peritoneal mast cells in vitro and in vivo: dependence of the in vitro effect on period of culture and comparisons of stem-cell factor with other mast cell-activating agents.

Authors:  A M Taylor; S J Galli; J W Coleman
Journal:  Immunology       Date:  1995-11       Impact factor: 7.397

Review 9.  Stem cell factor, a novel cutaneous growth factor for mast cells and melanocytes.

Authors:  J Grabbe; P Welker; E Dippel; B M Czarnetzki
Journal:  Arch Dermatol Res       Date:  1994       Impact factor: 3.017
  9 in total

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