Literature DB >> 1373406

Mapping of functional regions of Clostridium perfringens type A enterotoxin.

P C Hanna1, E U Wieckowski, T A Mietzner, B A McClane.   

Abstract

Studies were conducted to allow construction of an initial map of the structure-versus-function relationship of the Clostridium perfringens type A enterotoxin (CPE). Removal of the N-terminal 25 amino acids of CPE increased the primary cytotoxic effect of CPE but did not affect binding. CPE sequences required for at least four epitopes were also identified.

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Year:  1992        PMID： 1373406      PMCID： PMC257123          DOI： 10.1128/iai.60.5.2110-2114.1992

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  27 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Studies of Clostridium perfringens enterotoxin action at different temperatures demonstrate a correlation between complex formation and cytotoxicity.

Authors:  B A McClane; A P Wnek
Journal:  Infect Immun       Date:  1990-09       Impact factor: 3.441

3.  Primary action of Clostridium perfringens type A enterotoxin on HeLa and Vero cells in the absence of extracellular calcium: rapid and characteristic changes in membrane permeability.

Authors:  M Matsuda; K Ozutsumi; H Iwahashi; N Sugimoto
Journal:  Biochem Biophys Res Commun       Date:  1986-12-15       Impact factor: 3.575

4.  Characterization of membrane permeability alterations induced in Vero cells by Clostridium perfringens enterotoxin.

Authors:  B A McClane; J L McDonel
Journal:  Biochim Biophys Acta       Date:  1980-08-14

Review 5.  Clostridium perfringens enterotoxin.

Authors:  B A McClane; P C Hanna; A P Wnek
Journal:  Microb Pathog       Date:  1988-05       Impact factor: 3.738

6.  Isolation and function of a Clostridium perfringens enterotoxin fragment.

Authors:  Y Horiguchi; T Akai; G Sakaguchi
Journal:  Infect Immun       Date:  1987-12       Impact factor: 3.441

7.  Divalent cation involvement in the action of Clostridium perfringens type A enterotoxin. Early events in enterotoxin action are divalent cation-independent.

Authors:  B A McClane; A P Wnek; K I Hulkower; P C Hanna
Journal:  J Biol Chem       Date:  1988-02-15       Impact factor: 5.157

8.  Preliminary evidence that Clostridium perfringens type A enterotoxin is present in a 160,000-Mr complex in mammalian membranes.

Authors:  A P Wnek; B A McClane
Journal:  Infect Immun       Date:  1989-02       Impact factor: 3.441

9.  Molecular cloning of the 3' half of the Clostridium perfringens enterotoxin gene and demonstration that this region encodes receptor-binding activity.

Authors:  P C Hanna; A P Wnek; B A McClane
Journal:  J Bacteriol       Date:  1989-12       Impact factor: 3.490

10.  Production and characterization of monoclonal antibodies against Clostridium perfringens type A enterotoxin.

Authors:  A P Wnek; R J Strouse; B A McClane
Journal:  Infect Immun       Date:  1985-11       Impact factor: 3.441
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  20 in total

Review 1.  Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation.

Authors:  J Berkes; V K Viswanathan; S D Savkovic; G Hecht
Journal:  Gut       Date:  2003-03       Impact factor: 23.059

2.  A conjugated synthetic peptide corresponding to the C-terminal region of Clostridium perfringens type A enterotoxin elicits an enterotoxin-neutralizing antibody response in mice.

Authors:  T A Mietzner; J F Kokai-Kun; P C Hanna; B A McClane
Journal:  Infect Immun       Date:  1992-09       Impact factor: 3.441

Review 3.  Regulation of intestinal epithelial permeability by tight junctions.

Authors:  Takuya Suzuki
Journal:  Cell Mol Life Sci       Date:  2012-07-11       Impact factor: 9.261

4.  Noncytotoxic Clostridium perfringens enterotoxin (CPE) variants localize CPE intestinal binding and demonstrate a relationship between CPE-induced cytotoxicity and enterotoxicity.

Authors:  James G Smedley; Juliann Saputo; Jacquelyn C Parker; Mariano E Fernandez-Miyakawa; Susan L Robertson; Bruce A McClane; Francisco A Uzal
Journal:  Infect Immun       Date:  2008-05-27       Impact factor: 3.441

Review 5.  Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion.

Authors:  C L Sears; J B Kaper
Journal:  Microbiol Rev       Date:  1996-03

6.  Deletion analysis of the Clostridium perfringens enterotoxin.

Authors:  J F Kokai-Kun; B A McClane
Journal:  Infect Immun       Date:  1997-03       Impact factor: 3.441

7.  Identification of a Clostridium perfringens enterotoxin region required for large complex formation and cytotoxicity by random mutagenesis.

Authors:  J F Kokai-Kun; K Benton; E U Wieckowski; B A McClane
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.441

8.  Clostridium perfringens enterotoxin interacts with claudins via electrostatic attraction.

Authors:  Jun Kimura; Hiroyuki Abe; Shigeki Kamitani; Hirono Toshima; Aya Fukui; Masami Miyake; Yoichi Kamata; Yoshiko Sugita-Konishi; Shigeki Yamamoto; Yasuhiko Horiguchi
Journal:  J Biol Chem       Date:  2009-11-10       Impact factor: 5.157

9.  Cloning, nucleotide sequencing, and expression of the Clostridium perfringens enterotoxin gene in Escherichia coli.

Authors:  J R Czeczulin; P C Hanna; B A McClane
Journal:  Infect Immun       Date:  1993-08       Impact factor: 3.441

Review 10.  The interaction of Clostridium perfringens enterotoxin with receptor claudins.

Authors:  Archana Shrestha; Francisco A Uzal; Bruce A McClane
Journal:  Anaerobe       Date:  2016-04-16       Impact factor: 3.331
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