Literature DB >> 1372878

Prostatic intraepithelial neoplasia: a premalignant lesion.

M K Brawer1.   

Abstract

Putative premalignant changes in the prostate have been recognized for a number of years. A variety of synonyms have been given to the most commonly described lesion, one characterized by proliferation and dysplasia of the normal two cell layers lining prostatic acini and ductules. Currently, "prostatic intraepithelial neoplasia" (PIN) is the term most commonly used to describe this entity. In this review, the requirements for a premalignant lesion, the reason why PIN fulfills the majority of these requirements, and a detailed description of the morphologic and phenotypic similarities between PIN and carcinoma will be outlined. Finally, the clinical significance of PIN will be reviewed.

Entities:  

Mesh：

Year:  1992        PMID： 1372878     DOI： 10.1016/0046-8177(92)90104-b

Source DB:  PubMed          Journal:  Hum Pathol        ISSN： 0046-8177            Impact factor:   3.466


  16 in total

Review 1.  High grade prostatic intraepithelial neoplasia is a disease.

Authors:  M S Steiner
Journal:  Curr Urol Rep       Date:  2001-06       Impact factor: 3.092

2.  Integrin-dependent amplification of the G2 arrest induced by ionizing radiation.

Authors:  Celeste L Kremer; Monika Schmelz; Anne E Cress
Journal:  Prostate       Date:  2006-01-01       Impact factor: 4.104

3.  Bcl-2 immunoreactivity in prostate tumorigenesis in relation to prostatic intraepithelial neoplasia, grade, hormonal status, metastatic growth and survival.

Authors:  P Stattin; J E Damber; L Karlberg; H Nordgren; A Bergh
Journal:  Urol Res       Date:  1996

4.  Proliferative lesions of prostate: a multivariate approach to differential diagnosis.

Authors:  Fernanda de Barros Correia Cavalcanti; Venâncio Avancini Ferreira Alves; Julio Pereira; Cristina T Kanamura; Alda Wakamatsu; Luís Balthazar Saldanha
Journal:  Pathol Oncol Res       Date:  2005-07-01       Impact factor: 3.201

5.  Transient neonatal estrogen exposure to estrogen-deficient mice (aromatase knockout) reduces prostate weight and induces inflammation in late life.

Authors:  Joseph John Bianco; Stephen John McPherson; Hong Wang; Gail S Prins; Gail Petuna Risbridger
Journal:  Am J Pathol       Date:  2006-06       Impact factor: 4.307

6.  Differential expression of cytokeratin mRNA and protein in normal prostate, prostatic intraepithelial neoplasia, and invasive carcinoma.

Authors:  Y Yang; J Hao; X Liu; B Dalkin; R B Nagle
Journal:  Am J Pathol       Date:  1997-02       Impact factor: 4.307

7.  Alcohol exposure in utero increases susceptibility to prostate tumorigenesis in rat offspring.

Authors:  Sengottuvelan Murugan; Changqing Zhang; Sepideh Mojtahedzadeh; Dipak K Sarkar
Journal:  Alcohol Clin Exp Res       Date:  2013-07-26       Impact factor: 3.455

8.  Detection of the apoptosis-suppressing oncoprotein bc1-2 in hormone-refractory human prostate cancers.

Authors:  M Colombel; F Symmans; S Gil; K M O'Toole; D Chopin; M Benson; C A Olsson; S Korsmeyer; R Buttyan
Journal:  Am J Pathol       Date:  1993-08       Impact factor: 4.307

Review 9.  The significance of atypical adenomatous hyperplasia and prostatic intraepithelial neoplasia for the development of prostate carcinoma. An update.

Authors:  B G Helpap; D G Bostwick; R Montironi
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

Review 10.  High-grade prostatic intraepithelial neoplasia and prostate cancer risk reduction.

Authors:  Mitchell S Steiner
Journal:  World J Urol       Date:  2003-02-21       Impact factor: 4.226
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