| Literature DB >> 1372349 |
S Jann1, S Beretta, M Moggio, L Adobbati, G Pellegrini.
Abstract
Two patients were treated with treatment-resistant polymyositis with intravenous immunoglobulin over four days at a dose of 0.4 g/kg/day. Clinical recovery followed within two months. Serum creatine kinase (CK) activity decreased to normal, and a clear improvement in muscle strength was observed. One patient showed neither clinical relapses nor increase in serum CK activity after 20 months. The other showed a mild increase in serum CK activity after 24 months and was successfully retreated with intravenous immunoglobulin. There were no significant adverse side effects.Entities:
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Year: 1992 PMID: 1372349 PMCID: PMC488936 DOI: 10.1136/jnnp.55.1.60
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN: 0022-3050 Impact factor: 10.154