Literature DB >> 13723329

Specific inhibition of RHo(D) antibody by sialic acids.

M C DODD, N J BIGLEY, V B GEYER.   

Abstract

Agglutination of Rh(O)(D) erythrocytes by specific antiserum was inhibited by crude and crystalline N-acetylneuraminic acid, less inhibited by its glycoyl derivative, and weakly inhibited by its degradation product, N-acetyl-mannosamine, and by D-mannose. A brain ganglioside containing neuraminic acid and a Pseudomonas polysaccharide were even more inhibitory. Inhibition was specific for anti-D sera.

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Keywords:  ANTIBODIES; NEURAMINIC ACIDS/pharmacology

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Year:  1960        PMID: 13723329     DOI: 10.1126/science.132.3437.1398

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  1 in total

1.  Immunochemical properties of glycolipids.

Authors:  R O Brady
Journal:  J Am Oil Chem Soc       Date:  1966-02       Impact factor: 1.849

  1 in total

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