Literature DB >> 1371936

Rat alpha 1-microglobulin: co-expression in liver with the light chain of inter-alpha-trypsin inhibitor.

A Lindqvist1, T Bratt, M Altieri, W Kastern, B Akerström.   

Abstract

A 1162 bp rat liver cDNA clone encoding the immunoregulatory plasma protein alpha 1-microglobulin was isolated and sequenced. The open reading frame encoded a 349 amino acid polyprotein, including alpha 1-microglobulin, 182 amino acids, and bikunin, the light chain of the plasma protein inter-alpha-trypsin inhibitor, 145 amino acids. The alpha 1-microglobulin/bikunin mRNA was found only in the liver when different tissues were examined. Free alpha 1-microglobulin and a polyprotein, containing both alpha 1-microglobulin and inter-alpha-trypsin inhibitor epitopes, were found in the microsomal fraction from rat liver homogenates.

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Year:  1992        PMID： 1371936     DOI： 10.1016/0167-4781(92)90462-9

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  11 in total

Review 1.  The inter-alpha-inhibitor family: from structure to regulation.

Authors:  J P Salier; P Rouet; G Raguenez; M Daveau
Journal:  Biochem J       Date:  1996-04-01       Impact factor: 3.857

2.  Intracellular coupling of bikunin and the heavy chain of rat pre-alpha-inhibitor in COS-1 cells.

Authors:  A M Blom; M Thuveson; E Fries
Journal:  Biochem J       Date:  1997-11-15       Impact factor: 3.857

3.  Developmentally regulated transcription of the four liver-specific genes for inter-alpha-inhibitor family in mouse.

Authors:  J P Salier; P Chan; G Raguenez; T Zwingman; R P Erickson
Journal:  Biochem J       Date:  1993-11-15       Impact factor: 3.857

4.  Thrombin Cleavage of Inter-α-inhibitor Heavy Chain 1 Regulates Leukocyte Binding to an Inflammatory Hyaluronan Matrix.

Authors:  Aaron C Petrey; Carol A de la Motte
Journal:  J Biol Chem       Date:  2016-09-27       Impact factor: 5.157

5.  Adsorption of serum alpha-1-microglobulin onto biomaterials.

Authors:  M Santin; M Cannas; M A Wassall; S P Denyer
Journal:  J Mater Sci Mater Med       Date:  1998-03       Impact factor: 3.896

6.  Isolation and characterization of fibronectin-alpha 1-microglobulin complex in rat plasma.

Authors:  C Falkenberg; J J Enghild; I B Thøgersen; G Salvesen; B Akerström
Journal:  Biochem J       Date:  1994-08-01       Impact factor: 3.857

7.  Hierarchy and positive/negative interplays of the hepatocyte nuclear factors HNF-1, -3 and -4 in the liver-specific enhancer for the human alpha-1-microglobulin/bikunin precursor.

Authors:  P Rouet; G Raguenez; F Tronche; V Mfou'ou; J P Salier
Journal:  Nucleic Acids Res       Date:  1995-02-11       Impact factor: 16.971

8.  Factor IX Zutphen: a Cys18-->Arg mutation results in formation of a heterodimer with alpha 1-microglobulin and the inability to form a calcium-induced conformation.

Authors:  E G Wojcik; M van den Berg; I K van der Linden; S R Poort; R Cupers; R M Bertina
Journal:  Biochem J       Date:  1995-11-01       Impact factor: 3.857

9.  A Comparative Analysis of the Lipoprotein(a) and Low-Density Lipoprotein Proteomic Profiles Combining Mass Spectrometry and Mendelian Randomization.

Authors:  Raphaëlle Bourgeois; Arnaud Girard; Nicolas Perrot; Jakie Guertin; Patricia L Mitchell; Christian Couture; Clarisse Gotti; Sylvie Bourassa; Paolo Poggio; Elvira Mass; Romain Capoulade; Corey A Scipione; Audrey-Anne Després; Patrick Couture; Arnaud Droit; Philippe Pibarot; Michael B Boffa; Sébastien Thériault; Marlys L Koschinsky; Patrick Mathieu; Benoit J Arsenault
Journal:  CJC Open       Date:  2020-12-03

Review 10.  Human Anti-Oxidation Protein A1M--A Potential Kidney Protection Agent in Peptide Receptor Radionuclide Therapy.

Authors:  Jonas Ahlstedt; Thuy A Tran; Sven-Erik Strand; Magnus Gram; Bo Åkerström
Journal:  Int J Mol Sci       Date:  2015-12-18       Impact factor: 5.923
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