Literature DB >> 1371918

Cloning of murine and rat vascular cell adhesion molecule-1.

C Hession1, P Moy, R Tizard, P Chisholm, C Williams, M Wysk, L Burkly, K Miyake, P Kincade, R Lobb.   

Abstract

Vascular cell adhesion molecule-1 (VCAM1) is a member of the immunoglobulin (Ig) superfamily which interacts with the integrin very late antigen 4 (VLA4). We have cloned the cDNAs for both murine and rat VCAM1 from endotoxin-treated lung libraries. Both sequences encode proteins with seven extracellular Ig-like domains, which show 75.9% and 76.9% identity, respectively, with human VCAM1. Both murine and human cell lines show VLA4-dependent binding to COS cells transiently expressing murine and rat VCAM1. Two mAbs, M-K/1 and M-K/2, which recognize an antigen on murine bone marrow stromal cell lines, bind to murine VCAM1 expressed in COS cells and block VCAM1-dependent adhesion, confirming that these mAbs recognize murine VCAM1.

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1371918     DOI: 10.1016/0006-291x(92)91623-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  21 in total

1.  ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro.

Authors:  B J Steffen; G Breier; E C Butcher; M Schulz; B Engelhardt
Journal:  Am J Pathol       Date:  1996-06       Impact factor: 4.307

2.  Identification of the binding site in intercellular adhesion molecule 1 for its receptor, leukocyte function-associated antigen 1.

Authors:  K L Fisher; J Lu; L Riddle; K J Kim; L G Presta; S C Bodary
Journal:  Mol Biol Cell       Date:  1997-03       Impact factor: 4.138

Review 3.  Vascular cell adhesion molecule-1 expression and signaling during disease: regulation by reactive oxygen species and antioxidants.

Authors:  Joan M Cook-Mills; Michelle E Marchese; Hiam Abdala-Valencia
Journal:  Antioxid Redox Signal       Date:  2011-05-11       Impact factor: 8.401

4.  Pyrrolidine dithiocarbamate inhibits cytokine-induced VCAM-1 gene expression in rat cardiac myocytes.

Authors:  Y Hattori; K Akimoto; Y Murakami; K Kasai
Journal:  Mol Cell Biochem       Date:  1997-12       Impact factor: 3.396

5.  Lacrimal gland inflammation is responsible for ocular pathology in TGF-beta 1 null mice.

Authors:  N L McCartney-Francis; D E Mizel; M Frazier-Jessen; A B Kulkarni; J B McCarthy; S M Wahl
Journal:  Am J Pathol       Date:  1997-11       Impact factor: 4.307

6.  Cytokine induction of an alternatively spliced murine vascular cell adhesion molecule (VCAM) mRNA encoding a glycosylphosphatidylinositol-anchored VCAM protein.

Authors:  R W Terry; L Kwee; J F Levine; M A Labow
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

7.  Regulation of endothelial VCAM-1 expression in murine cardiac grafts. Expression of allograft endothelial VCAM-1 can be manipulated with antagonist of IFN-alpha or IL-4 and is not required for allograft rejection.

Authors:  S D Bergese; E H Huang; R P Pelletier; M B Widmer; R M Ferguson; C G Orosz
Journal:  Am J Pathol       Date:  1995-07       Impact factor: 4.307

8.  The role of ICAM-1/LFA-1 and VCAM-1/VLA-4 interactions on T helper 2 cytokine production by lung T cells of Toxocara canis-infected mice.

Authors:  M Takamoto; M Isobe; K Sugane
Journal:  Immunology       Date:  1998-11       Impact factor: 7.397

9.  Selectin- and integrin-mediated T-lymphocyte rolling and arrest on TNF-alpha-activated endothelium: augmentation by erythrocytes.

Authors:  R J Melder; L L Munn; S Yamada; C Ohkubo; R K Jain
Journal:  Biophys J       Date:  1995-11       Impact factor: 4.033

10.  Tumorigenicity of IL-1alpha- and IL-1beta-deficient fibrosarcoma cells.

Authors:  Irina Nazarenko; Rachid Marhaba; Eli Reich; Elena Voronov; Mario Vitacolonna; Dagmar Hildebrand; Elena Elter; Mohini Rajasagi; Ron N Apte; Margot Zöller
Journal:  Neoplasia       Date:  2008-06       Impact factor: 5.715

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.