Literature DB >> 13711835

The excretion of sodium 6-(2,6-dimethoxybenzamidopenicillanate) monohydrate in rats.

P M HARRISON, J A WHITE, G T STEWART.   

Abstract

The excretion of sodium 6-(2:6 dimethoxybenzamido) penicillanate monohydrate has been studied. When injected intramuscularly it was rapidly excreted in the bile and urine of rats, but only in trace amounts in the faeces. The excretion products in the bile (2 to 3% of the dose) and urine (26-84% of the dose) are microbiologically active. The product in the bile may be in conjugated form.

Entities:  

Keywords:  PENICILLIN/metabolism

Mesh：

Substances：

Year:  1960        PMID： 13711835      PMCID： PMC1482271          DOI： 10.1111/j.1476-5381.1960.tb00284.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  4 in total

1.  Bacteriological studies on a new penicillin-BRL. 1241.

Authors:  G N ROLINSON; S STEVENS; F R BATCHELOR; J C WOOD; E B CHAIN
Journal:  Lancet       Date:  1960-09-10       Impact factor: 79.321

2.  Absorption and excretion of a new antibiotic (BRL 1241).

Authors:  E T KNUDSEN; G N ROLINSON
Journal:  Br Med J       Date:  1960-09-03

3.  A New Synthetic Penicillin.

Authors:  A H Douthwaite; J A Trafford
Journal:  Br Med J       Date:  1960-09-03

4.  Microbiological studies on sodium 6-(2, 6 dimethoxybenzamido) penicillanate monohydrate (BRL 1241) in vitro and in patients.

Authors:  G T STEWART
Journal:  Br Med J       Date:  1960-09-03
  4 in total
  1 in total

1.  Pharmacology of methicillin.

Authors:  P ACRED; D M BROWN; D H TURNER; D WRIGHT
Journal:  Br J Pharmacol Chemother       Date:  1961-08
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.