Literature DB >> 137073

Purification of carcinoembryonic antigen by removal of contaminating mucopolysaccharides.

D G Pritchard, C W Todd.   

Abstract

The fraction of carcinoembryonic antigen preparations not bound by concanavalin A was studied. A significant portion of this nonbound fraction of low antigenic activity was shown to be mucopolysaccharides by gas chromatography-mass spectrometry, cellulose acetate strip electrophoresis, and depolymerization by bovine testicular hyaluronidase.

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Year:  1976        PMID： 137073

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  5 in total

1.  Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family.

Authors:  R J Paxton; G Mooser; H Pande; T D Lee; J E Shively
Journal:  Proc Natl Acad Sci U S A       Date:  1987-02       Impact factor: 11.205

2.  Binding of Escherichia coli and Salmonella strains to members of the carcinoembryonic antigen family: differential binding inhibition by aromatic alpha-glycosides of mannose.

Authors:  H G Leusch; Z Drzeniek; Z Markos-Pusztai; C Wagener
Journal:  Infect Immun       Date:  1991-06       Impact factor: 3.441

3.  Serum-derived carcinoembryonic antigen (CEA) activates fibroblasts to induce a local re-modeling of the extracellular matrix that favors the engraftment of CEA-expressing tumor cells.

Authors:  Aws Abdul-Wahid; Marzena Cydzik; Nicholas W Fischer; Aaron Prodeus; John E Shively; Anne Martel; Samira Alminawi; Zeina Ghorab; Neil L Berinstein; Jean Gariépy
Journal:  Int J Cancer       Date:  2018-08-09       Impact factor: 7.396

4.  Carcinoembryonic antigen is anchored to membranes by covalent attachment to a glycosylphosphatidylinositol moiety: identification of the ethanolamine linkage site.

Authors:  S A Hefta; L J Hefta; T D Lee; R J Paxton; J E Shively
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

5.  Extraction of CEA from tumour tissue, foetal colon and patients' sera, and the effect of perchloric acid.

Authors:  P A Keep; B A Leake; G T Rogers
Journal:  Br J Cancer       Date:  1978-02       Impact factor: 7.640
  5 in total

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