Literature DB >> 1370534

Generation of a subtype-specific neutralization epitope in foot-and-mouth disease virus of a different subtype.

J Hernández1, M A Martínez, E Rocha, E Domingo, M G Mateu.   

Abstract

An epitope involved in neutralization of foot-and-mouth disease virus (FMDV) of subtype C3 was generated by a single amino acid replacement in VP1 of FMDV of subtype C1. The replacement [Ser (139)----Ile, in the immunodominant site A] was consistently found in those FMDV C1 Santa Pau-Sp/70 mutants resistant to neutralization by monoclonal antibody (MAb) SD6 (specific for most C1 viruses) that acquired the capacity to be neutralized by MAb 7AB5 (specific for C3 viruses).

Entities:  

Mesh:

Substances:

Year:  1992        PMID: 1370534     DOI: 10.1099/0022-1317-73-1-213

Source DB:  PubMed          Journal:  J Gen Virol        ISSN: 0022-1317            Impact factor:   3.891


  8 in total

Review 1.  Molecular evolution of aphthoviruses.

Authors:  E Domingo; M G Mateu; C Escarmís; E Martínez-Salas; D Andreu; E Giralt; N Verdaguer; I Fita
Journal:  Virus Genes       Date:  1995       Impact factor: 2.332

2.  Evolution subverting essentiality: dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus.

Authors:  M A Martínez; N Verdaguer; M G Mateu; E Domingo
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-24       Impact factor: 11.205

3.  A simple and rapid colloidal gold-based immunochromatogarpic strip test for detection of FMDV serotype A.

Authors:  Tao Jiang; Zhong Liang; Wei-wei Ren; Juan Chen; Xiao-ying Zhi; Guang-yu Qi; Xiang-tao Liu; Xue-peng Cai
Journal:  Virol Sin       Date:  2011-02-18       Impact factor: 4.327

4.  Amino acid variation within the fusion protein of respiratory syncytial virus subtype A and B strains during annual epidemics in South Africa.

Authors:  Elizabeth Agenbach; Caroline T Tiemessen; Marietjie Venter
Journal:  Virus Genes       Date:  2005-03       Impact factor: 2.332

5.  Antigenic heterogeneity of a foot-and-mouth disease virus serotype in the field is mediated by very limited sequence variation at several antigenic sites.

Authors:  M G Mateu; J Hernández; M A Martínez; D Feigelstock; S Lea; J J Pérez; E Giralt; D Stuart; E L Palma; E Domingo
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

6.  Evolution of the capsid protein genes of foot-and-mouth disease virus: antigenic variation without accumulation of amino acid substitutions over six decades.

Authors:  M A Martínez; J Dopazo; J Hernández; M G Mateu; F Sobrino; E Domingo; N J Knowles
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103

7.  Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction.

Authors:  N Verdaguer; M G Mateu; D Andreu; E Giralt; E Domingo; I Fita
Journal:  EMBO J       Date:  1995-04-18       Impact factor: 11.598

8.  Genetic Basis of Antigenic Variation of SAT3 Foot-And-Mouth Disease Viruses in Southern Africa.

Authors:  Lorens Maake; William T Harvey; Lia Rotherham; Pamela Opperman; Jacques Theron; Richard Reeve; Francois F Maree
Journal:  Front Vet Sci       Date:  2020-09-08
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.