| Literature DB >> 1370534 |
J Hernández1, M A Martínez, E Rocha, E Domingo, M G Mateu.
Abstract
An epitope involved in neutralization of foot-and-mouth disease virus (FMDV) of subtype C3 was generated by a single amino acid replacement in VP1 of FMDV of subtype C1. The replacement [Ser (139)----Ile, in the immunodominant site A] was consistently found in those FMDV C1 Santa Pau-Sp/70 mutants resistant to neutralization by monoclonal antibody (MAb) SD6 (specific for most C1 viruses) that acquired the capacity to be neutralized by MAb 7AB5 (specific for C3 viruses).Entities:
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Year: 1992 PMID: 1370534 DOI: 10.1099/0022-1317-73-1-213
Source DB: PubMed Journal: J Gen Virol ISSN: 0022-1317 Impact factor: 3.891