Literature DB >> 13704253

Effects of 3-methylcholanthrene and phenobarbital on amino acid incorporation into protein.

H V GELBOIN, L SOKOLOFF.   

Abstract

Treatment of rats with methylcholanthrene and phenobarbital, two compounds known to enhance microsomal enzyme activity, stimulates the incorporation of free or soluble ribonucleic acid bound amino acid into proteins of cell-free liver preparations. Mitochondria, microsomes, and cell sap all contribute to the methylcholanthrene effect on the incorporation of free amino acid.

Entities:  

Keywords:  AMINO ACIDS/metabolism; METHYLCHOLANTHRENE/pharmacology; PHENOBARBITAL/pharmacology; PROTEINS/metabolism

Mesh：

Substances：

Year:  1961        PMID： 13704253     DOI： 10.1126/science.134.3479.611

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Effect of polychlorinated biphenyls (Phenoclor DP6) on in vivo protein and RNA synthesis in rat liver.

Authors:  J F Narbonne
Journal:  Bull Environ Contam Toxicol       Date:  1979-09       Impact factor: 2.151

2.  Effect of polychlorinated biphenyls (Phenoclor DP6) on in vitro amino acid incorporation into liver proteins.

Authors:  J F Narbonne
Journal:  Bull Environ Contam Toxicol       Date:  1979-02       Impact factor: 2.151

3.  METHYLCHOLANTHRENE-INDUCED CHANGES IN RAT LIVER NUCLEAR RNA.

Authors:  L A LOEB; H V GELBOIN
Journal:  Proc Natl Acad Sci U S A       Date:  1964-11       Impact factor: 11.205

4.  [Enzyme induction and increase of endoplasmic reticulum in liver cells during phenobarbital (Luminal) therapy].

Authors:  H REMMER; H J MERKER
Journal:  Klin Wochenschr       Date:  1963-03-15

5.  Studies on azo-dye carcinogenesis in rat liver. The effect of 4-dimethylamino-3'-methylazobenzene on the incorporation of [C]leucine into rat-liver microsomal protein.

Authors:  A O Hawtrey; V Schirren; J Dijkstra
Journal:  Biochem J       Date:  1963-07       Impact factor: 3.857

6.  The effect of phenobarbitone on protein synthesis by liver polyribosomes in fed and starved rats.

Authors:  G Ragnotti; M G Aletti
Journal:  Biochem J       Date:  1975-01       Impact factor: 3.857

7.  Effect of some polycyclic aromatic hydrocarbons on protein synthesis in vitro.

Authors:  J Hradec
Journal:  Biochem J       Date:  1967-10       Impact factor: 3.857

8.  [On 2-benzolsulfonylamino-5(beta-methoxy-ethoxy)-pyrimidine (glycodiazine. V. In vitro and in vivo experiments on the action of phenylethylbarbituric acid (Luminal) on the metabolism and blood sugar reducing effect of glycodiazine].

Authors:  E Gerhards; K H Kolb; P E Schulze
Journal:  Naunyn Schmiedebergs Arch Pharmakol Exp Pathol       Date:  1966

9.  Effect of parathion on liver microsomal enzyme activites induced by organochlorine pesticides and drugs in female rats.

Authors:  W E MacDonald; J MacQueen; W B Deichmann; T Hamill; K Copsey
Journal:  Int Arch Arbeitsmed       Date:  1970

Review 10.  Nutritional disturbances of protein metabolism in the liver.

Authors:  H Sidransky
Journal:  Am J Pathol       Date:  1976-09       Impact factor: 4.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.