| Literature DB >> 13702952 |
S GAINES, M LANDY, G EDSALL, A D MANDEL, R J TRAPANI, A S BENENSON.
Abstract
A study was made of the efficacy of various antityphoid immunizing agents in immunizing chimpanzees against typhoid fever produced by feeding viable S. typhosa. It was found that both acetone-killed and heat-killed, phenol-preserved typhoid vaccines were effective in protecting against infection induced with either homologous or heterologous strains of typhoid bacilli. Purified O antigen induced no discernible protection, but some immunity was afforded by the administration of purified Vi antigen.Entities:
Keywords: TYPHOID/immunology
Mesh:
Substances:
Year: 1961 PMID: 13702952 PMCID: PMC2137464 DOI: 10.1084/jem.114.3.327
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307