Literature DB >> 1370020

Cystic fibrosis--the way forward from the gene.

J R Dorin1, D J Porteous.   

Abstract

Cloning of the cystic fibrosis (CF) gene and elucidation of the physiological functions of the encoded protein is a triumph, not only for molecular biology, but also for people affected by CF. For them, not only is there now the possibility of screening for the commonest mutations, but they may also look forward to the prospect of improved therapies being developed.

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Year:  1991        PMID: 1370020     DOI: 10.1016/0167-7799(91)90188-N

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN: 0167-7799            Impact factor:   19.536


  1 in total

1.  Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells.

Authors:  J R Dorin; P Dickinson; E Emslie; A R Clarke; L Dobbie; M L Hooper; S Halford; B J Wainwright; D J Porteous
Journal:  Transgenic Res       Date:  1992-03       Impact factor: 2.788

  1 in total

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