| Literature DB >> 13692932 |
Abstract
Tobacco mosaic virus-infectious nucleic acid causes a color shift when combined with acridine orange, methylene blue, and safranine. A high concentration of acridine orange inactivates infectious nucleic acid even in darkness, while a mixture of nucleic acid with a low concentration of the dye must be exposed to visible light prior to inoculation for inactivation to occur.Entities:
Keywords: DYES/chemistry; NUCLEIC ACIDS/chemistry; VIRUSES/chemistry
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Substances:
Year: 1960 PMID: 13692932 DOI: 10.1126/science.132.3442.1840
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728