Literature DB >> 13692295

Phagocytized platelets: a source of lipids in human thrombi and atherosclerotic plaques.

A B CHANDLER, R A HAND.   

Abstract

Phagocytosis of lipid-rich platelets by monocytes and the transformation of such cells into lipophages containing fat was observed in human thrombi. The lipophages are similar to lipophages in atherosclerotic plaques. This observation supports the idea that some atherosclerotic plaques are organized mural thrombi.

Entities:  

Keywords:  ARTERIOSCLEROSIS/blood; BLOOD PLATELETS; LIPIDS/blood; PHAGOCYTOSIS; THROMBOSIS/blood

Mesh：

Substances：

Year:  1961        PMID： 13692295     DOI： 10.1126/science.134.3483.946

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

1.  The occurrence of microthrombi on the aortic endothelium of swine.

Authors:  H D GEISSINGER; J F MUSTARD; H C ROWSELL
Journal:  Can Med Assoc J       Date:  1962-08-25       Impact factor: 8.262

2.  Atherosclerotic metamorphosis of autologous pulmonary thromboemboli in the rabbit.

Authors:  R A HAND; A B CHANDLER
Journal:  Am J Pathol       Date:  1962-04       Impact factor: 4.307

Review 3.  Emerging roles for platelets as immune and inflammatory cells.

Authors:  Craig N Morrell; Angela A Aggrey; Lesley M Chapman; Kristina L Modjeski
Journal:  Blood       Date:  2014-02-28       Impact factor: 22.113

4.  New mechanism for foam cell generation in atherosclerotic lesions.

Authors:  L K Curtiss; A S Black; Y Takagi; E F Plow
Journal:  J Clin Invest       Date:  1987-08       Impact factor: 14.808

5.  Resolution and organization of platelet-rich mural thrombi in carotid arteries of swine.

Authors:  L Jorgensen; H C Rowsell; T Hovig; J F Mustard
Journal:  Am J Pathol       Date:  1967-11       Impact factor: 4.307

6.  Phagocytosis of platelets by leukocytes in artificial thrombi and in platelet aggregates induced by adenosine diphosphate.

Authors:  K Shirasawa; A B Chandler
Journal:  Am J Pathol       Date:  1971-05       Impact factor: 4.307

7.  Platelets, fibroblasts, and inflammation: tissue reactions to platelets injected subcutaneously.

Authors:  P W Braunstein; H F Cuénoud; I Joris; G Majno
Journal:  Am J Pathol       Date:  1980-04       Impact factor: 4.307

8.  Platelets and atherogenesis. I. Augmentation of cholesterol atherogenesis in the rabbit by a phlebotomy programme designed to induce thrombocytosis.

Authors:  P Cohen; H L McCombs
Journal:  Br J Exp Pathol       Date:  1967-06

9.  Atherosclerosis, platelets and thrombosis in acute ischaemic heart disease.

Authors:  Lina Badimon; Teresa Padró; Gemma Vilahur
Journal:  Eur Heart J Acute Cardiovasc Care       Date:  2012-04

10.  Protective effect of Tulbaghia violacea Harv. on aortic pathology, tissue antioxidant enzymes and liver damage in diet-induced atherosclerotic rats.

Authors:  Olubukola S Olorunnisola; Graeme Bradley; Anthony J Afolayan
Journal:  Int J Mol Sci       Date:  2012-10-08       Impact factor: 5.923
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