Literature DB >> 13679803

Regulatory T cells control the development of allergic disease and asthma.

Dale T Umetsu1, Omid Akbari, Rosemarie H Dekruyff.   

Abstract

The role of T(H)2 cells in the pathogenesis of allergy and asthma has been well described. However, the immunologic mechanisms that downmodulate and protect against the development of these disorders are poorly characterized. A spectrum of CD4+ T cells, including T(H)1 cells, T(H)3 cells, regulatory T cells, CD25+ T cells, and natural killer T cells might play a critical role in regulating these diseases and are discussed in this review.

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Year:  2003        PMID： 13679803

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN： 0091-6749            Impact factor:   10.793


  38 in total

Review 1.  Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6.

Authors:  Svetlana Chapoval; Preeta Dasgupta; Nicolas J Dorsey; Achsah D Keegan
Journal:  J Leukoc Biol       Date:  2010-03-24       Impact factor: 4.962

2.  Gene-environment interaction effects on the development of immune responses in the 1st year of life.

Authors:  Sabine Hoffjan; Dan Nicolae; Irina Ostrovnaya; Kathy Roberg; Michael Evans; Daniel B Mirel; Lori Steiner; Karen Walker; Peter Shult; Ronald E Gangnon; James E Gern; Fernando D Martinez; Robert F Lemanske; Carole Ober
Journal:  Am J Hum Genet       Date:  2005-02-22       Impact factor: 11.025

3.  Effects of systemic versus local administration of corticosteroids on mucosal tolerance.

Authors:  Jerome Kerzerho; Daniela Wunsch; Natacha Szely; Hellmuth-Alexander Meyer; Lisa Lurz; Lars Röse; Ulrich Wahn; Omid Akbari; Philippe Stock
Journal:  J Immunol       Date:  2011-11-21       Impact factor: 5.422

4.  Heme oxygenase-1 attenuates ovalbumin-induced airway inflammation by up-regulation of foxp3 T-regulatory cells, interleukin-10, and membrane-bound transforming growth factor- 1.

Authors:  Zhen-Wei Xia; Li-Qing Xu; Wen-Wei Zhong; Jing-Jing Wei; Ning-Li Li; Jie Shao; Yun-Zhu Li; Shan-Chang Yu; Zi-Li Zhang
Journal:  Am J Pathol       Date:  2007-11-08       Impact factor: 4.307

5.  Regulatory activity of human CD4 CD25 T cells depends on allergen concentration, type of allergen and atopy status of the donor.

Authors:  Iris Bellinghausen; Bettina König; Ingo Böttcher; Jürgen Knop; Joachim Saloga
Journal:  Immunology       Date:  2005-09       Impact factor: 7.397

6.  TLR2/6 stimulation of the rat lung: effects on lymphocyte subsets, natural killer cells and dendritic cells in different parts of the air-conducting compartments and at different ages.

Authors:  Reinhard Pabst; Deniz Durak; Anna Roos; Anke Lührmann; Thomas Tschernig
Journal:  Immunology       Date:  2008-06-19       Impact factor: 7.397

7.  Schistosoma mansoni antigens modulate experimental allergic asthma in a murine model: a major role for CD4+ CD25+ Foxp3+ T cells independent of interleukin-10.

Authors:  Lucila G G Pacífico; Fábio A V Marinho; Cristina T Fonseca; Michele M Barsante; Vanessa Pinho; Policarpo A Sales-Junior; Luciana S Cardoso; Maria Ilma Araújo; Edgar M Carvalho; Geovanni D Cassali; Mauro M Teixeira; Sergio C Oliveira
Journal:  Infect Immun       Date:  2008-09-29       Impact factor: 3.441

8.  Antagonism of airway tolerance by endotoxin/lipopolysaccharide through promoting OX40L and suppressing antigen-specific Foxp3+ T regulatory cells.

Authors:  Wei Duan; Takanori So; Michael Croft
Journal:  J Immunol       Date:  2008-12-15       Impact factor: 5.422

9.  Repeated bouts of aerobic exercise enhance regulatory T cell responses in a murine asthma model.

Authors:  Thomas Lowder; Kari Dugger; Jessy Deshane; Kim Estell; Lisa M Schwiebert
Journal:  Brain Behav Immun       Date:  2009-09-23       Impact factor: 7.217

10.  Effects of dehydroepiandrosterone on Th2 cytokine production in peripheral blood mononuclear cells from asthmatics.

Authors:  Inseon S Choi; Yong Cui; Young Ah Koh; Hyun Chul Lee; Yong Bum Cho; Young Ho Won
Journal:  Korean J Intern Med       Date:  2008-12       Impact factor: 2.884
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