Literature DB >> 1367950

Globin gene switching: a paradigm or what?

T Enver1, D R Greaves.   

Abstract

The delineation of the beta-globin locus control region has led to a new understanding of the developmental regulation of the beta-globin gene cluster. It now seems that globin gene switching is effected through the sequential and mutually exclusive interaction of the locus control region with the embryonic, fetal and adult stage specific globin genes.

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Year:  1991        PMID: 1367950     DOI: 10.1016/s0958-1669(05)80108-9

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  3 in total

1.  The mouse beta-globin locus control region: hypersensitive sites 3 and 4.

Authors:  G Jiménez; K B Gale; T Enver
Journal:  Nucleic Acids Res       Date:  1992-11-11       Impact factor: 16.971

2.  Activation of the beta-globin locus control region precedes commitment to the erythroid lineage.

Authors:  G Jiménez; S D Griffiths; A M Ford; M F Greaves; T Enver
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-15       Impact factor: 11.205

3.  Regulation of embryonic/fetal globin genes by nuclear hormone receptors: a novel perspective on hemoglobin switching.

Authors:  A Filipe; Q Li; S Deveaux; I Godin; P H Roméo; G Stamatoyannopoulos; V Mignotte
Journal:  EMBO J       Date:  1999-02-01       Impact factor: 11.598

  3 in total

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