Literature DB >> 1367930

Yeast artificial chromosomes (YACs) and the analysis of complex genomes.

R Anand1.   

Abstract

The development of yeast artificial chromosome (YAC) cloning vectors capable of carrying several hundred kilobase-pairs of DNA insert has greatly facilitated the study of complex genomes, and the cloning of large genes as single fragments. In addition, the ability to manipulate YAC sequences by homologous recombination makes this system extremely useful for the generation of disease models.

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Year:  1992        PMID： 1367930     DOI： 10.1016/0167-7799(92)90165-r

Source DB:  PubMed          Journal:  Trends Biotechnol        ISSN： 0167-7799            Impact factor:   19.536


  2 in total

1.  Construction of a designer chromosome in tobacco.

Authors:  K G Campbell; E A Wernsman; W P Fitzmurice; J A Burns
Journal:  Theor Appl Genet       Date:  1994-02       Impact factor: 5.699

2.  Assessment of aryl hydrocarbon receptor complex interactions using pBEVY plasmids: expressionvectors with bi-directional promoters for use in Saccharomyces cerevisiae.

Authors:  C A Miller; M A Martinat; L E Hyman
Journal:  Nucleic Acids Res       Date:  1998-08-01       Impact factor: 16.971
  2 in total

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