Literature DB >> 13675771

10-Hydroxy-delta 2-decenoic acid, an antibiotic found in royal jelly.

M S BLUM, A F NOVAK, S TABER.   

Abstract

10-Hydroxy-Delta(2)-decenoic acid, the major component of the lipide fraction of royal jelly, exhibits antibiotic activity against many bacteria and fungi. This fatty acid is less than one-fourth as active as penicillin against Micrococcus pyogenes and less than one-fifth as active as chlortetracycline against Escherichia coli. It also slows the growth rate of Neurospora sitophila and some unidentified molds. The salt of this compound is considerably less active than the free acid.

Entities:  

Keywords:  ANTIBIOTICS/determination; BEES; FATTY ACIDS

Mesh:

Substances:

Year:  1959        PMID: 13675771     DOI: 10.1126/science.130.3373.452

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  28 in total

1.  The antimicrobial activity of some insect extracts possessing juvenile hormone activity.

Authors:  R A SLEPECKY; L I GILBERT
Journal:  Experientia       Date:  1962-01-15

2.  ANTIBIOTIC PROPERTIES OF ACRYLIC ACID, A FACTOR IN THE GASTROINTESTINAL ANTIBIOSIS OF POLAR MARINE ANIMALS.

Authors:  J M Sieburth
Journal:  J Bacteriol       Date:  1961-07       Impact factor: 3.490

3.  Connective tissue growth factor, a regulator related with 10-hydroxy-2-decenoic acid down-regulate MMPs in rheumatoid arthritis.

Authors:  Jian-guang Wang; Jian Ruan; Chun-yang Li; Jian-min Wang; Yan Li; Wei-tao Zhai; Wei Zhang; Hui Ye; Nian-han Shen; Kang-fu Lei; Xiu-fang Chen; Xin-yu Yang
Journal:  Rheumatol Int       Date:  2011-08-18       Impact factor: 2.631

4.  Pollinator attraction in a sexually deceptive orchid by means of unconventional chemicals.

Authors:  Manfred Ayasse; Florian P Schiestl; Hannes F Paulus; Fernando Ibarra; Wittko Francke
Journal:  Proc Biol Sci       Date:  2003-03-07       Impact factor: 5.349

5.  Royal jelly enhances migration of human dermal fibroblasts and alters the levels of cholesterol and sphinganine in an in vitro wound healing model.

Authors:  Juyoung Kim; Youngae Kim; Hyejeong Yun; Hyemin Park; Sun Yeou Kim; Kwang-Gill Lee; Sang-Mi Han; Yunhi Cho
Journal:  Nutr Res Pract       Date:  2010-10-26       Impact factor: 1.926

6.  Inhibitory mechanism of 10-hydroxy-trans-2-decenoic acid (royal jelly acid) against lipopolysaccharide- and interferon-β-induced nitric oxide production.

Authors:  Tsuyoshi Sugiyama; Keita Takahashi; Akihiro Kuzumaki; Shunji Tokoro; Paola Neri; Hiroshi Mori
Journal:  Inflammation       Date:  2013-04       Impact factor: 4.092

7.  Why not be a queen? Regioselectivity in mandibular secretions of honeybee castes.

Authors:  E Plettner; G R Sutherland; K N Slessor; M L Winston
Journal:  J Chem Ecol       Date:  1995-07       Impact factor: 2.626

8.  Antimicrobial activity of some N-substituted amides of long-chain fatty acids.

Authors:  A F Novak; J M Solar; R R Mod; F C Magne; E L Skau
Journal:  Appl Microbiol       Date:  1969-12

9.  The efficacy of topical royal jelly on healing of diabetic foot ulcers: a double-blind placebo-controlled clinical trial.

Authors:  Mansour Siavash; Saeideh Shokri; Sepehr Haghighi; Mohammad Ali Shahtalebi; Ziba Farajzadehgan
Journal:  Int Wound J       Date:  2013-04-08       Impact factor: 3.315

10.  10-Hydroxy-2-decenoic acid, a major fatty acid from royal jelly, inhibits VEGF-induced angiogenesis in human umbilical vein endothelial cells.

Authors:  Hiroshi Izuta; Yuichi Chikaraishi; Masamitsu Shimazawa; Satoshi Mishima; Hideaki Hara
Journal:  Evid Based Complement Alternat Med       Date:  2007-10-22       Impact factor: 2.629

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