Literature DB >> 1367520

Reversion of L-lysine inhibition of penicillin G biosynthesis by 6-oxopiperidine-2-carboxylic acid in Penicillium chrysogenum PQ-96.

W Kurzatkowski1, J D Kurzatkowski, J Filipek, J Solecka, W Kuryłowicz.   

Abstract

6-Oxopiperidine-2-carboxylic acid (OCA; cyclic alpha-aminoadipic acid) reverses the L-lysine inhibition of penicillin G production by Penicillium chrysogenum PQ-96. The reaction probably depends on the recovery of L-alpha-aminoadipic acid for penicillin G production from OCA.

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Year:  1990        PMID: 1367520     DOI: 10.1007/bf00170067

Source DB:  PubMed          Journal:  Appl Microbiol Biotechnol        ISSN: 0175-7598            Impact factor:   4.813


  5 in total

1.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

2.  Theoretical conversion yields for penicillin synthesis.

Authors:  C L Cooney; F Acevedo
Journal:  Biotechnol Bioeng       Date:  1977-10       Impact factor: 4.530

3.  Lysine control of penicillin biosynthesis.

Authors:  P S Masurekar; A L Demain
Journal:  Can J Microbiol       Date:  1972-07       Impact factor: 2.419

4.  Lysine regulation of penicillin biosynthesis in low-producing and industrial strains of Penicillium chrysogenum.

Authors:  J M Luengo; G Revilla; J R Villanueva; J F Martín
Journal:  J Gen Microbiol       Date:  1979-11

5.  Association of 6-oxo-piperidine-2-carboxylic acid with penicillin V. Production on Penicillium chrysogenum fermentations.

Authors:  S P Brundidge; F C Gaeta; D J Hook; C Sapino; R P Elander; R B Morin
Journal:  J Antibiot (Tokyo)       Date:  1980-11       Impact factor: 2.649

  5 in total
  1 in total

Review 1.  Molecular regulation of beta-lactam biosynthesis in filamentous fungi.

Authors:  A A Brakhage
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

  1 in total

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