Literature DB >> 13668540

Molecular structural factors in competitive inhibition of sugar transport.

P G LEFEVRE.   

Abstract

The high potency of phloretin as a competitive inhibitor of the human red cell's monosaccharide transport system is not shared by any of several molecular fragments of phloretin, but is duplicated in certain artificial estrogens resembling phloretin in respect to the spacing between terminal phenolic -OH groups. Related molecules which are slightly less extendible are comparatively inactive.

Entities:  

Keywords:  ERYTHROCYTES/metabolism; MONOSACCHARIDES/in blood; PROPIOPHENONES/effects

Mesh：

Substances：

Year:  1959        PMID： 13668540     DOI： 10.1126/science.130.3367.104

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  The effect of naringenin on the intestinal and renal transport of organic solutes.

Authors:  J W Robinson; M L'Herminier; H G Claudet
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-05       Impact factor: 3.000

2.  Influence of estrogenic pesticides on membrane integrity and membrane transfer of monosaccharide into the human red cell.

Authors:  R L Ingermann
Journal:  Bull Environ Contam Toxicol       Date:  1989-09       Impact factor: 2.151

3.  The response of isolated cat muscle spindles to passive stretch.

Authors:  I A Boyd; J Ward
Journal:  J Physiol       Date:  1969-02       Impact factor: 5.182

4.  Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro.

Authors:  H G Coore; P J Randle
Journal:  Biochem J       Date:  1964-10       Impact factor: 3.857

5.  Glucose transport into spinach chloroplasts.

Authors:  G Schäfer; U Heber
Journal:  Plant Physiol       Date:  1977-08       Impact factor: 8.340

6.  The permeability of lysosomes to sugars. Effect of diethylstilbestrol on the osmotic activation of lysosomes induced by glucose.

Authors:  M Jadot; S Wattiaux-De Coninck; R Wattiaux
Journal:  Biochem J       Date:  1989-09-15       Impact factor: 3.857

7.  The effect of temperature on the competitive inhibition of glucose transfer in human erythrocytes by phenolphthalein, phloretin and stilboestrol.

Authors:  M L Forsling; W F Widdas
Journal:  J Physiol       Date:  1968-02       Impact factor: 5.182

8.  FGT-1-mediated glucose uptake is defective in insulin/IGF-like signaling mutants in Caenorhabditis elegans.

Authors:  Shun Kitaoka; Anthony D Morielli; Feng-Qi Zhao
Journal:  FEBS Open Bio       Date:  2016-04-21       Impact factor: 2.693

9.  Factors influencing glucose flux and the effect of insulin in cultured human cells.

Authors:  R J Hay; J Paul
Journal:  J Gen Physiol       Date:  1967-07       Impact factor: 4.086
  9 in total

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