Literature DB >> 1366615

Production of monoclonal antibodies by hybridoma cells in a flat sheet membrane bioreactor.

J Hagedorn1, F Kargi.   

Abstract

The purpose of this study was to investigate hybridoma growth and monoclonal antibody formation in a flat sheet membrane bioreactor. The effects of several different molecular weight cutoff membranes on growth and antibody formation were investigated. Nutrient and toxic product diffusion through the membranes were quantified, and the kinetic and physical constants of the system were determined.

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Year:  1990        PMID: 1366615     DOI: 10.1021/bp00003a011

Source DB:  PubMed          Journal:  Biotechnol Prog        ISSN: 1520-6033


  2 in total

1.  Effect of endogenous proteins on growth and antibody productivity in hybridoma batch cultures.

Authors:  P J Farrell; N Kalogerakis; L A Behie
Journal:  Cytotechnology       Date:  1994       Impact factor: 2.058

2.  Hybridoma culture in polyether sponge with bovine whey.

Authors:  J Capiaumont; C Legrand; B Dousset; F Belleville; P Nabet
Journal:  In Vitro Cell Dev Biol Anim       Date:  1995-06       Impact factor: 2.416

  2 in total

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