Literature DB >> 13665284

The trifluoromethyl group in medicinal chemistry.

H L YALE.   

Abstract

Keywords:  DRUGS; METHANE

Mesh：

Substances：

Year:  1959        PMID： 13665284     DOI： 10.1021/jm50003a001

Source DB:  PubMed          Journal:  J Med Pharm Chem        ISSN： 0095-9065


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  17 in total

1.  Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus.

Authors:  Kwaku Kyei-Baffour; Haroon Mohammad; Mohamed N Seleem; Mingji Dai
Journal:  Bioorg Med Chem       Date:  2019-03-19       Impact factor: 3.641

2.  Overlapping binding sites of structurally different antiarrhythmics flecainide and propafenone in the subunit interface of potassium channel Kv2.1.

Authors:  Michael Madeja; Wibke Steffen; Ivana Mesic; Bojan Garic; Boris S Zhorov
Journal:  J Biol Chem       Date:  2010-08-13       Impact factor: 5.157

3.  Opposing orientations of the anti-psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulin.

Authors:  Michael D Feldkamp; Lokesh Gakhar; Nisha Pandey; Madeline A Shea
Journal:  Proteins       Date:  2015-03-25

4.  Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists.

Authors:  Xin Chen; John D McCorvy; Matthew G Fischer; Kyle V Butler; Yudao Shen; Bryan L Roth; Jian Jin
Journal:  J Med Chem       Date:  2016-11-16       Impact factor: 7.446

5.  Synthesis and applications of S-(trifluoromethyl)-2,8-bis(trifluoromethoxy)dibenzothiophenium triflate (Umemoto reagent IV).

Authors:  Sagar R Mudshinge; Gerald B Hammond; Teruo Umemoto
Journal:  J Fluor Chem       Date:  2022-07-03       Impact factor: 2.226

6.  Cytotoxic Activity of Piperazin-2-One-Based Structures: Cyclic Imines, Lactams, Aminophosphonates, and Their Derivatives.

Authors:  Jakub Iwanejko; Mahzeiar Samadaei; Matthias Pinter; Daniel Senfter; Sibylle Madlener; Andrzej Kochel; Nataliya Rohr-Udilova; Elżbieta Wojaczyńska
Journal:  Materials (Basel)       Date:  2021-04-22       Impact factor: 3.623

Review 7.  Radiosynthesis of [18)F]trifluoroalkyl groups: scope and limitations.

Authors:  V T Lien; P J Riss
Journal:  Biomed Res Int       Date:  2014-07-10       Impact factor: 3.411

8.  Drug-Clinical Agent Molecular Hybrid: Synthesis of Diaryl(trifluoromethyl)pyrazoles as Tubulin Targeting Anticancer Agents.

Authors:  Neha Hura; Afsana Naaz; Shweta S Prassanawar; Sankar K Guchhait; Dulal Panda
Journal:  ACS Omega       Date:  2018-02-19

9.  Difluoromethanesulfonyl hypervalent iodonium ylides for electrophilic difluoromethylthiolation reactions under copper catalysis.

Authors:  Sadayuki Arimori; Okiya Matsubara; Masahiro Takada; Motoo Shiro; Norio Shibata
Journal:  R Soc Open Sci       Date:  2016-05-25       Impact factor: 2.963

10.  Non-covalent interactions involving halogenated derivatives of capecitabine and thymidylate synthase: a computational approach.

Authors:  Adhip Rahman; Mohammad Mazharol Hoque; Mohammad A K Khan; Mohammed G Sarwar; Mohammad A Halim
Journal:  Springerplus       Date:  2016-02-24
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