Literature DB >> 13662576

The stability of endogenous corticotrophin in rat blood in vitro.

J R HODGES, J VERNIKOS.   

Abstract

Endogenous corticotrophin is stable in blood in vitro for periods of up to 1 hr. at 4 degrees and 22 degrees , and in plasma for at least 24 hr. at -15 degrees . Estimates of plasma corticotrophin concentration provide less consistent results than assays done on whole blood. The optimal conditions for storing blood prior to the determination of its corticotrophin concentration are discussed.

Entities:  

Keywords:  ACTH/in blood

Mesh:

Substances:

Year:  1959        PMID: 13662576      PMCID: PMC1481785          DOI: 10.1111/j.1476-5381.1959.tb01386.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  11 in total

1.  Increased adrenocorticotrophic hormone in the sera of acutely scorbutic guinea-pigs.

Authors:  B E CLAYTON; J E HAMMANT; P ARMITAGE
Journal:  J Endocrinol       Date:  1957-07       Impact factor: 4.286

2.  The effect of adrenalectomy on the circulating level of adrenocorticotrophic hormone in the rat.

Authors:  G S COX; J R HODGES; J VERNIKOS
Journal:  J Endocrinol       Date:  1958-07       Impact factor: 4.286

3.  The level of adrenocorticotrophin in the plasma of normal and adrenalectomized rats.

Authors:  A M BARRETT; J R HODGES
Journal:  J Endocrinol       Date:  1956-07       Impact factor: 4.286

4.  Blood ACTH in the stressed adrenalectomized rat after intravenous injection of hydrocortisone.

Authors:  K L SYDNOR
Journal:  Endocrinology       Date:  1955-02       Impact factor: 4.736

5.  Corticotropic activity of human blood.

Authors:  J PARIS; M UPSON; R G SPRAGUE; R M SALASSA; A ALBERT
Journal:  J Clin Endocrinol Metab       Date:  1954-06       Impact factor: 5.958

6.  Inactivation of adrenotropic hormone (ACTH) by plasma.

Authors:  M REISS; F E BADRICK; I D K HALKERSTON; C PLAICE
Journal:  Nature       Date:  1951-08-04       Impact factor: 49.962

7.  Biological half-life of endogenous ACTH.

Authors:  K L SYDNOR; G SAYERS
Journal:  Proc Soc Exp Biol Med       Date:  1953 Aug-Sep

8.  Increase the formation and secretion of ACTH following adrenalectomy.

Authors:  C A GEMZELL; D C VAN DYKE; C A TOBIAS; H M EVANS
Journal:  Endocrinology       Date:  1951-09       Impact factor: 4.736

9.  Inactivation of adrenocorticotropic hormone in vitro by tissues.

Authors:  I I GESCHWIND; C H LI
Journal:  Endocrinology       Date:  1952-02       Impact factor: 4.736

10.  Fate and excretion of adrenocorticotrophic hormone.

Authors:  J B RICHARDS; G SAYERS
Journal:  Proc Soc Exp Biol Med       Date:  1951-05
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