| Literature DB >> 13662566 |
R T BRITTAIN, B G CHESHER, H O COLLIER, J J GRIMSHAW.
Abstract
Suxamethonium, like acetylcholine, causes contracture of the isolated rectus abdominis muscle of the frog, whereas laudexium antagonizes this effect. These actions may be used to assay both drugs with reasonable speed and fiducial limits, provided that changes in responsiveness of the preparation during the course of assay are met by suitable design and analysis. Small quantities of suxamethonium and laudexium may be assayed in certain body fluids.Entities:
Keywords: MUSCLE RELAXANTS/determination; MUSCLES/effect of drugs on; SUCCINYLCHOLINE/determination
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Year: 1959 PMID： 13662566 PMCID： PMC1481804 DOI： 10.1111/j.1476-5381.1959.tb01376.x
Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826